Results 131 to 140 of about 3,685,182 (335)
Methods of quantifying a mass mortality event in freshwater wildlife within the river ecosystem
MethodsXThis study introduces a comprehensive method for quantifying mass mortality events in freshwater wildlife, exemplified by the ecological disaster in the Odra River in 2022.
Dominik Marchowski +5 more
doaj +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Testing the Flux Rope Paradigm for Coronal Mass Ejections Using a Three-spacecraft Encounter Event
The Astrophysical JournalWe present a 3D morphological and field reconstruction of a coronal mass ejection (CME) from 2023 November 28, which hits three spacecraft near 1 au: Wind at Earth’s L1 Lagrange point, STEREO-A with a longitudinal separation of 6 $\mathop{.}\limits ...
Brian E. Wood, Phillip Hess
doaj +1 more source
A mass bleaching event involving clionaid sponges [PDF]
Coral Reefs, 2016 M. Hill, C. Walter, E. Bartels
openaire +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Staff assignment policies for a mass casualty event queuing network
Annals of Operations Research, 2019 Emmett J. Lodree, N. Altay, R. Cook
semanticscholar +1 more source