Results 91 to 100 of about 9,300 (265)

A Review of Recent Advances in Discretization Methods, a Posteriori Error Analysis, and Adaptive Algorithms for Numerical Modeling in Geosciences

Oil & Gas Science and Technology, 2014
Two research subjects in geosciences which lately underwent significant progress are treated in this review. In the first part, we focus on one key ingredient for the numerical approximation of the Darcy flow problem, namely the discretization of ...
Di Pietro Daniele A., Vohralík Martin
doaj   +1 more source

Piecewise structural equation modelling in ecology: common pitfalls and best practices for causal inference

Oikos, EarlyView.
Structural equation modelling (SEM) has become a cornerstone tool in ecology for testing hypotheses about causal relationships and disentangling direct and indirect effects. However, its growing use has led to frequent conceptual and methodological misapplications.
Álvaro Gaytán
wiley   +1 more source

Adaptive Semidiscrete Finite Element Methods for Semilinear Parabolic Integrodifferential Optimal Control Problem with Control Constraint

Journal of Applied Mathematics, 2013
The aim of this work is to study the semidiscrete finite element discretization for a class of semilinear parabolic integrodifferential optimal control problems. We derive a posteriori error estimates in L2(J;L2(Ω))-norm and L2(J;H1(Ω))-norm for both the
Zuliang Lu
doaj   +1 more source

Accelerating the prioritisation of plant species with underexplored medicinal potential: The pm4mp (Phylogenetic Methods for Medicinal Plants) R package

PLANTS, PEOPLE, PLANET, EarlyView.
Medicinal plants used in ethnobotanical traditions to treat or prevent diseases have gained renewed interest for their largely untapped potential in drug discovery. In this study, we developed and tested novel methods to prioritise plant species based on their unexplored medicinal potential. By enabling researchers to target the most promising species,
Giovanni Zecca, Elisa Toini, Massimo Labra, Fabrizio Grassi   +3 more
wiley   +1 more source

Molecular Basis for Uracil‐DNA‐Glycosylase to Identify DNA Damage in the Nucleosome

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The DNA base‐excision repair (BER) pathway is initiated by a glycosylase, such as uracil‐DNA‐glycosylase (UDG), which identifies and removes a wrong base incorporated in the DNA sequence. The very early steps in the identification of the DNA damage are crucial to the correct initiation of the repair chain, and become even more complex when ...
Safwen Ghediri, Ralf Blossey, Fabrizio Cleri   +2 more
wiley   +1 more source

Adaptive Finite Element Method for Optimal Control Problem Governed by Linear Quasiparabolic Integrodifferential Equations

Abstract and Applied Analysis, 2012
The mathematical formulation for a quadratic optimal control problem governed by a linear quasiparabolic integrodifferential equation is studied. The control constrains are given in an integral sense: Uad={u∈X;∫ΩUu⩾0, t∈[0,T]}.
Wanfang Shen, Hua Su
doaj   +1 more source

A Posteriori Error Estimates for Fully Discrete Finite Element Method for Generalized Diffusion Equation with Delay. [PDF]

J Sci Comput, 2020
Wang W, Yi L, Xiao A.
europepmc   +1 more source

Multisite Analysis of Vancomycin Concentration Predictions in a Bayesian Software in Adult and Pediatric Patients With and Without Acute Kidney Injury. [PDF]

Pharmacotherapy
ABSTRACT Background Bayesian software programs are recommended for area under the concentration‐time curve (AUC)‐guided vancomycin monitoring, but hesitancy remains for patients with acute kidney injury (AKI). Here, we assessed agreement between population pharmacokinetic model‐based Bayesian predictions and observed vancomycin concentrations in ...
Hughes MA, Pearson JC, Hughes JH.
europepmc   +2 more sources

In planta fluxapyroxad gradients from seed treatment differentially select fungicide‐sensitive and reduced‐sensitive genotypes of Pyrenophora teres f. maculata

Pest Management Science, EarlyView.
Spatial concentration gradients of seed‐applied fluxapyroxad within barley create heterogeneous exposure environments, driving differential suppression of succinate dehydrogenase inhibitor‐sensitive Pyrenophora teres f. maculata isolates and enrichment of reduced‐sensitive genotypes, thereby shaping within‐host fungicide resistance selection dynamics ...
Arundhati Singh, Elizabeth Czislowski, Mark Gibberd, Kefei Chen, Francisco J Lopez‐Ruiz, M Jordi Muria‐Gonzalez   +5 more
wiley   +1 more source

EnKF and expectation‐maximization based parameter estimation of a convective gravity‐wave parameterization using Strateole 2 constant‐level balloon data

Quarterly Journal of the Royal Meteorological Society, EarlyView.
An offline methodology is applied to estimate parameters of a convective gravity‐wave scheme using momentum flux (MF) observations from constant‐level balloons (left panels: pdfs of east and west MFs in green from observations and black from EnKF). The approach integrates an ensemble Kalman filter with an expectation‐maximization algorithm and permits ...
F. Lott, P. Tandeo, M. Pulido, D. Bardet
wiley   +1 more source