Results 191 to 200 of about 9,300 (265)

A prospective feasibility study evaluating the implementation of model-informed precision dosing in critically ill children. [PDF]

open access: yesFront Pharmacol
Bayraktar I   +7 more
europepmc   +1 more source

Methods for Uncertainty Quantification in Dictionary Matching to Advance Reliability of Quantitative MRI

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 4, Page 1956-1971, October 2026.
ABSTRACT Aims Purpose: Dictionary matching is a standard tool in quantitative MRI (qMRI), but typically lacks uncertainty quantification (UQ). This is critical when advanced reconstructions (e.g., compressed sensing, deep learning) introduce complex‐valued, spatially varying, and temporally correlated noise that violates standard assumptions of ...
Brian Toner   +7 more
wiley   +1 more source

Denoising of ASL Data Using Deep Learning Priors Generated From Distribution Remapping

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 4, Page 1972-1982, October 2026.
ABSTRACT Purpose To develop an effective deep learning (DL)–based method to denoise arterial spin labeling (ASL) data. Methods Conventional DL–based ASL denoising methods often suffer from overfitting and poor generalization when training data are limited.
Ziyang Xu   +9 more
wiley   +1 more source

Preclinical Pharmacokinetic‐Pharmacodynamic Modeling of Antibody Nanoconjugates for Breast Cancer Treatment

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 10, October 2026.
ABSTRACT Over the past 5 years, the number of antibody–drug conjugates (ADCs) entering the oncology market has surged. By contrast, the clinical use of immunoliposomes—nanoparticles that also employ antibodies as targeting agents (i.e., antibody–nanoconjugates, ANCs)—has yet to receive approval.
Anne Rodallec   +4 more
wiley   +1 more source

Simulation-Based Evaluation of Busulfan Sampling Strategies in Adults and Adolescents Undergoing Allogeneic Hematopoietic Stem Cell Transplantation. [PDF]

open access: yesJ Clin Pharmacol
Tan Z   +6 more
europepmc   +1 more source

Multi‐Objective Bayesian Co‐Optimization of Parameterized Moving Horizon Estimation and Model Predictive Control

open access: yesInternational Journal of Robust and Nonlinear Control, Volume 36, Issue 15, Page 7193-7213, October 2026.
ABSTRACT This paper proposes a Machine Learning (ML)‐enabled estimator‐controller design framework, in which a parameterized Model Predictive Controller (MPC) and a parameterized Moving Horizon Estimator (MHE) are jointly refined using Bayesian Optimization (BO).
Hossein Nejatbakhsh Esfahani   +1 more
wiley   +1 more source

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