Results 171 to 180 of about 9,369 (262)

Preclinical Pharmacokinetic‐Pharmacodynamic Modeling of Antibody Nanoconjugates for Breast Cancer Treatment

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 10, October 2026.
ABSTRACT Over the past 5 years, the number of antibody–drug conjugates (ADCs) entering the oncology market has surged. By contrast, the clinical use of immunoliposomes—nanoparticles that also employ antibodies as targeting agents (i.e., antibody–nanoconjugates, ANCs)—has yet to receive approval.
Anne Rodallec   +4 more
wiley   +1 more source

Multi‐Objective Bayesian Co‐Optimization of Parameterized Moving Horizon Estimation and Model Predictive Control

open access: yesInternational Journal of Robust and Nonlinear Control, Volume 36, Issue 15, Page 7193-7213, October 2026.
ABSTRACT This paper proposes a Machine Learning (ML)‐enabled estimator‐controller design framework, in which a parameterized Model Predictive Controller (MPC) and a parameterized Moving Horizon Estimator (MHE) are jointly refined using Bayesian Optimization (BO).
Hossein Nejatbakhsh Esfahani   +1 more
wiley   +1 more source

An Integrated Gradient Boosting Machine Approach With Fisher's Discriminant Analysis: Empirical Assessment on Five Benchmark Datasets and Simulations

open access: yesStatistical Analysis and Data Mining: An ASA Data Science Journal, Volume 19, Issue 5, October 2026.
ABSTRACT The aim of this study is to assess the impact of different dimensionality reduction techniques—specifically Principal Component Analysis (PCA) and Fisher's Linear Discriminant Analysis (LDA)—on the classification performance of Gradient Boosting Machines (GBM).
Giulio Enzo Donninelli   +1 more
wiley   +1 more source

Automatic GNSS Coordinate Time Series Analysis for Very Large Networks

open access: yesEarth and Space Science, Volume 13, Issue 10, October 2026.
Abstract We present a new algorithm, AutoCF, for automatically constructing coordinate functions (CFs) for continuously operating GNSS reference stations (CORSs). The iterative algorithm alternates between application of LASSO and Ridge Regression methods, with hyperparameters successively tightened with each iteration to more judiciously scrutinize ...
Richard A. Bennett   +3 more
wiley   +1 more source

Direct and indirect genetic effects of birthweight predisposition on child DNA methylation at birth. [PDF]

open access: yesEpigenetics
Creasey N   +6 more
europepmc   +1 more source

Neural Surrogate HMC: On Using Neural Likelihoods for Hamiltonian Monte Carlo in Simulation‐Based Inference

open access: yesJournal of Geophysical Research: Machine Learning and Computation, Volume 3, Issue 5, October 2026.
Abstract Bayesian inference methods such as Markov Chain Monte Carlo (MCMC) typically require repeated computations of the likelihood function, but in some scenarios, this is infeasible and alternative methods are needed. Simulation‐based inference methods address this problem by using machine learning to amortize computations.
L. M. Wolniewicz, P. Sadowski, C. Corti
wiley   +1 more source

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