Results 211 to 220 of about 401,417 (282)

The AI-based phase-seeding (AI-PhaSeed) method: early applications and statistical analysis. [PDF]

J Appl Crystallogr
Carrozzini B, Fedele F, Moliterni A, De Caro L, Cuocci C, Giannini C, Caliandro R, Altomare A.   +7 more
europepmc   +1 more source

Improving Genotype Imputation in High‐Dimensional Pharmacogenomics Using Multiple Imputation: Evaluation with Machine Learning Approaches

Clinical Pharmacology &Therapeutics, EarlyView.
Multiple imputation is well‐established for handling missing data, yet its use in high‐dimensional genetic datasets remains limited. Using pharmacokinetic tuberculosis simulations and SNP data (1000 Genomes Project), we compared machine learning (ML) and traditional approaches (e.g., mean imputation and complete‐case analysis) for imputation and ...
Innocent G. Asiimwe, Tao You, Daniel F. Carr, Munir Pirmohamed, Geraint Davies, Andrea L. Jorgensen, on behalf of the UNITE4TB Consortium   +6 more
wiley   +1 more source

Effectiveness of Machine Learning in Detecting Vessels Encapsulating Tumor Clusters in Hepatocellular Carcinoma: Systematic Review and Meta-Analysis.

J Med Internet Res
Shui H, Wu W, Xie Z, Yang B, Deng J, Tang D.   +5 more
europepmc   +1 more source

Scalable inference and identifiability of kinetic parameters for transcriptional bursting from single cell data. [PDF]

Bioinformatics
Gu J, Laszik N, Miles CE, Allard J, Downing TL, Read EL.   +5 more
europepmc   +1 more source

Population Pharmacokinetics of Clesrovimab in Preterm and Full‐Term Infants

Clinical Pharmacology &Therapeutics, EarlyView.
Clesrovimab is a half‐life extended monoclonal antibody targeting the respiratory syncytial virus fusion protein. Three studies (phase Ib/IIa [MK‐1654‐002], phase IIb/III [CLEVER], and phase III [SMART]) were conducted to evaluate the efficacy, safety, and pharmacokinetics (PK) of clesrovimab in infants.
Ziheng Hu, Farina Hellmann, Xiaowei Zang, Nele Plock, Keyur Parmar, Radha A. Railkar, S. Y. Amy Cheung, Brian M. Maas, Ferdous Gheyas   +8 more
wiley   +1 more source

Ethical clinical trial design and differences in treatment effects. [PDF]

Bull World Health Organ
Lewis RJ, Viele K, Ndomondo-Sigonda M, Sow S, Temfack E, Strub-Wourgaft N.   +5 more
europepmc   +1 more source

Saving the Planet, Saving the Team, and Shouting Down the Messenger: The Relationships Among Narcissism Subtypes and Misreporting of Emissions

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines how three subtypes of narcissism—communal, antagonistic, and collective—relate to sustainability team members' willingness to misreport greenhouse gas (GHG) emissions. Using survey‐based online experiments with experienced professionals from the United States and United Kingdom, we assess whether narcissistic traits predict
Eric N. Johnson, Matthias Sohn
wiley   +1 more source

The sense of agency in near and far space: where do we stand? [PDF]

Neurosci Conscious
Kong G, Vernet M, Farnè A.
europepmc   +1 more source

The Role of Social Media in Exposing Greenwashing: Consumer Sentiments and Discussions

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines consumer responses to greenwashing on social media, with a focus on X (formerly Twitter), where exaggerated or deceptive environmental claims are subject to heightened public scrutiny. As sustainability becomes a pressing concern, consumers are increasingly holding companies accountable for their environmental messaging ...
Mitra Salimi, Francesco Tuscolano, Outi Niininen, Outi Uusitalo   +3 more
wiley   +1 more source

A powerful framework for differential co-expression analysis of general risk factors. [PDF]

Bioinformatics
Bass AJ, Cutler DJ, Epstein MP.
europepmc   +1 more source