Results 61 to 70 of about 3,554,294 (233)
Production of a sterile species via active-sterile mixing: an exactly solvable model
, 2007 The production of a sterile species via active-sterile mixing in a thermal medium is studied in an exactly solvable model. The \emph{exact} time evolution of the sterile distribution function is determined by the dispersion relations and damping rates ...
A. Boyarsky +10 more
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Influência da minhoca no manejo de microbacias hidrográficas
Agropecuária Catarinense, 1996 É normalmente dito que as minhocas exercem influência positiva sobre as plantas, por causa do seu desempenho ao melhorar o solo. Os efeitos benéficos de minhocas sobre as plantas têm sido extensivamente estudados e provados nas áreas agrícolas e ...
Masato Kobiyama
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Explosive events on sub-arcsecond scale in IRIS observations: a case study
, 2014 We present study of a typical explosive event (EE) at sub-arcsecond scale witnessed by strong non-Gaussian profiles with blue- and red-shifted emission of up to 150 km/s seen in the transition-region Si IV 1402.8 \AA, and the chromospheric Mg II k 2796.4
Doyle, J. G. +5 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
The mass of Albireo Aa and the nature of Albireo AB: New aspects from Gaia DR2
, 2018 Aims: We aim to clarify the nature of Albireo AB and specifically to decipher whether it is an optical or physical pair. We also try to determine the mass of Albireo Aa.
Anton, R., Bastian, U.
core +1 more source