Results 61 to 70 of about 3,567,709 (290)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Influência da minhoca no manejo de microbacias hidrográficas

Agropecuária Catarinense, 1996
É normalmente dito que as minhocas exercem influência positiva sobre as plantas, por causa do seu desempenho ao melhorar o solo. Os efeitos benéficos de minhocas sobre as plantas têm sido extensivamente estudados e provados nas áreas agrícolas e ...
Masato Kobiyama
doaj  

Lessons learned in implementing an Alcoholics Anonymous peer support model in Lilongwe, Malawi

Journal of Public Health in Africa
No abstract available.
Katherine Boyd, Chifundo S. Tepeka, Thomas W. Psyata, Tommy Mthepheya, Thuy Bui, Caroline Kensler, Phillip Wagner   +6 more
doaj   +1 more source

Nuclear modification at sqrt{s_{NN}}=17.3 GeV, measured at NA49

, 2008
Transverse momentum spectra up to 4.5 GeV/c were measured around midrapidity in Pb+Pb reactions at sqrt{s_{NN}}=17.3 GeV, for pi^{+/-}, p, pbar and K^{+/-}, by the NA49 experiment.
A. László, C. Alt, C. Alt, C. Alt, C. Alt, D. Antreasyan, L. Ruan, M. M. Aggarwal, M. M. Aggarwal, S. Afanasiev, S. S. Adler, S. S. Adler, S. S. Adler, S. S. Adler, X. N. Wang   +14 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Spiral-shaped wavefronts in a sunspot umbra

, 2018
Solar active regions show a wide variety of oscillatory phenomena. The presence of the magnetic field leads to the appearance of several wave modes, whose behavior is determined by the sunspot thermal and magnetic structure.
Felipe, T., Khomenko, E., Kuckein, C., Thaler, I.   +3 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source