Results 51 to 60 of about 525,841 (269)

TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching. [PDF]

open access: yes, 2015
The AAA+ family ATPase TRIP13 is a key regulator of meiotic recombination and the spindle assembly checkpoint, acting on signaling proteins of the conserved HORMA domain family.
Corbett, Kevin D   +5 more
core   +2 more sources

DNA‐Origami‐Assembled Rhodium Nanoantennas for Deep‐UV Label‐Free Single‐Protein Detection

open access: yesAdvanced Functional Materials, EarlyView.
Deep‐UV autofluorescence of single proteins in DNA origami‐based rhodium nanoantennas. Precisely positioned within the plasmonic nanogap, proteins retain their native state while their intrinsic emission is strongly amplified, enabling label‐free single‐molecule detection and opening new opportunities for highly sensitive and specific biosensing ...
Nicco Corduri   +8 more
wiley   +1 more source

Regulation of AI Simulation Software in Resolving Disputes Through ADR: A Focus on Outer Space Commerce Law

open access: yesAdvanced Space Law
The increasing commercialization of space, coupled with the increasing number of private parties, cross-border commercial agreements, and complex technical disputes, has created a need for effective dispute resolution mechanisms.
Asra Tufail Dahraj
doaj   +1 more source

Retrospective review of abdominal aortic aneurysm deaths in New Zealand: what proportion of deaths is potentially preventable by a screening programme in the contemporary setting?

open access: yesBMJ Open, 2019
Objectives To describe the proportions of people dying from abdominal aortic aneurysm (AAA) who might have benefited from a formal screening programme for AAA.Design Retrospective cross-sectional review of deaths.Setting and study populations All AAA ...
Wing Cheuk Chan   +3 more
doaj   +1 more source

Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA [PDF]

open access: yes, 2013
In eukaryotes, the Cdt1-bound replicative helicase core MCM2-7 is loaded onto DNA by the ORC-Cdc6 ATPase to form a prereplicative complex (pre-RC) with an MCM2-7 double hexamer encircling DNA.
A Costa   +68 more
core   +1 more source

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

open access: yesAdvanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu   +4 more
wiley   +1 more source

The dimension of a variety

open access: yes, 2006
We invent the notion of a {\it dimension of a variety} $V$ as the cardinality of all its proper {\it derived} subvarieties (of the same type). The dimensions of varieties of lattices, varieties of regular bands and other general algebraic structures are ...
Cya In B¸edlewo   +2 more
core   +2 more sources

Opportunities of Semiconducting Oxide Nanostructures as Advanced Luminescent Materials in Photonics

open access: yesAdvanced Materials, EarlyView.
The review discusses the challenges of wide and ultrawide bandgap semiconducting oxides as a suitable material platform for photonics. They offer great versatility in terms of tuning microstructure, native defects, doping, anisotropy, and micro‐ and nano‐structuring. The review focuses on their light emission, light‐confinement in optical cavities, and
Ana Cremades   +7 more
wiley   +1 more source

2D Nanomaterials Toward Function‐Ready Superlubricity in Advanced Microsystems

open access: yesAdvanced Materials, EarlyView.
A unified framework links structural and transformation superlubricity with microsystem functions and deployment requirements. Mechanisms, device architectures, integration strategies, AI‐guided discovery, and benchmarking protocols are connected to define function‐ready superlubricity in advanced microsystems.
Yushan Geng, Jun Yang, Yong Yang
wiley   +1 more source

PCSK9, a novel immune and ferroptosis related gene in abdominal aortic aneurysm neck

open access: yesScientific Reports, 2023
The gene expression profile of abdominal aortic aneurysm (AAA) neck is not fully understood. The etiology of AAA is considered to be related to atherosclerosis and the inflammatory response, involving congenital, genetic, metabolic, and other factors ...
Junli Zhuang   +10 more
doaj   +1 more source

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