Results 81 to 90 of about 133,810 (254)

Variability Tests for Intrinsic Absorption Lines in Quasar Spectra

open access: yes, 2003
Quasar spectra have a variety of absorption lines whose origins range from energetic winds expelled from the central engines to unrelated, intergalactic clouds.
Arnaud M.   +11 more
core   +1 more source

Real‐World Outcomes of Nivolumab and Ipilimumab in Metastatic Melanoma as Third Line and Beyond

open access: yesInternational Journal of Cancer, EarlyView.
Progression after anti‐PD‐1‐based therapy is a predominant scenario in metastatic melanoma. However, real‐world data informing treatment of metastatic melanoma in later lines remains scarce. This retrospective nationwide, population‐based cohort study shows in a real‐world setting that nivolumab plus ipilimumab can induce durable responses beyond the ...
Yago Garitaonaindia   +11 more
wiley   +1 more source

Overview of Policies, Guidelines, and Standards for Active Assisted Living Data Exchange: Thematic Analysis

open access: yesJMIR mHealth and uHealth, 2020
BackgroundA primary concern for governments and health care systems is the rapid growth of the aging population. To provide a better quality of life for the elderly, researchers have explored the use of wearables, sensors, actuators, and mobile health ...
Fadrique, Laura X   +5 more
doaj   +1 more source

Disrupted Brain Structure and Function in Alzheimer's Disease Patients With Behavioral and Psychological Symptoms

open access: yesiNew Medicine, EarlyView.
ABSTRACT Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent in Alzheimer's disease (AD), but the underlying mechanisms are unclear. This study aims to elucidate the neuropathological mechanisms underlying BPSD by investigating gray matter volume (GMV) and brain connectivity in AD patients with and without BPSD.
Xuerui Pang   +8 more
wiley   +1 more source

Outflows and the Physical Properties of Quasars

open access: yes, 2007
We have investigated a sample of 5088 quasars from the Sloan Digital Sky Survey Second Data Release in order to determine how the frequency and properties of broad absorptions lines (BALs) depend on black hole mass, bolometric luminosity, Eddington ...
Brian Scoggins   +8 more
core   +1 more source

Evaluating Brief Behavioural Activation for depression in adolescents with acquired brain injury using a single‐case experimental design

open access: yesJCPP Advances, EarlyView.
Abstract Background Adolescents who have had an acquired brain injury (ABI) commonly experience depression. Brief Behavioural Activation (Brief BA) is a successful, values‐based intervention for managing depression in neurotypical adolescents. This study investigated the effectiveness of Brief BA, using a single‐case experimental design, with ...
Conor R. O’Brien   +4 more
wiley   +1 more source

Data‐driven subtyping reveals heterogeneous functional brain development trajectories in preterm infants

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract Brain development in preterm infants shows marked heterogeneity, often obscured by group‐level analyses. Between the group‐level and the individual difference, subgroup can model the heterogeneity of early developmental trajectories. To characterize this, we analyzed longitudinal functional connectome data from 90 preterm infants (scanned at ...
Jing Yu   +8 more
wiley   +1 more source

Dasatinib and quercetin prevent alveolar bone loss in aged mice

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Recent findings have associated alveolar bone loss (ABL) with the presence of senescent cells. Aging and the accumulation of senescent cells are associated with a pro‐inflammatory environment which may exacerbate tissue damage.
Luisa S. Battistelli   +7 more
wiley   +1 more source

Distinct Brain Drivers and Shared Cerebello–Cortical Input in ADCY5 and SGCE Hyperkinetic Movements

open access: yesMovement Disorders, EarlyView.
Resting‐state fMRI and effective connectivity revealed distinct cerebellar–basal ganglia–cortical interactions in ADCY5 (MxMD‐ADCY5) and SGCE (MYC/DYT‐SGCE) related movement disorders. The cerebellum modulated cortex directly in MYC/DYT‐SGCE, but indirectly via basal ganglia‐cerebellar projections in MxMD‐ADCY5, which also showed reduced subthalamic ...
Clément Tarrano   +33 more
wiley   +1 more source

Research and calibration of Acoustic Sensors in ice within the SPATS (South Pole Acoustic Test Setup) project

open access: yes, 2010
We present development work aiming towards a large scale ice-based hybrid detector including acoustic sensors for the detection of neutrinos in the GZK range.
Bevan   +8 more
core   +1 more source

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