Persistencia de medicamentos biológicos durante ocho años en pacientes con artritis reumatoide y espondiloartritis [PDF]
, 2019 Objective: To calculate the persistence, over a period of eight years, the retention rate of first and second-line of treatment with biological agents in patients with rheumatoid arthritis, spondyloarthritis and psoriatic arthritis and to compare ...
Balsa, Alejandro +5 more
core +3 more sources
PLoS ONE, 2022 BackgroundsTreating asthmatic rheumatoid arthritis patients with abatacept has been shown to associate with better control of asthma symptoms. However, the mechanism behind that is not investigated.MethodsOvalbumin (OVA)- sensitized BALB/c female mice ...
Maha Fahad Alenazy +15 more
doaj +1 more source
an interim analysis from the observational, prospective ACTION study [PDF]
, 2015 Background The emergence of new therapies for the treatment of rheumatoid arthritis (RA), the paucity of head-to-head studies, and the heterogeneous nature of responses to current biologics highlight the need for the identification of prognostic factors ...
Alten, Rieke +12 more
core +1 more source
Prognostic factors for abatacept retention in patients who received at least one prior biologic agent: an interim analysis from the observational, prospective ACTION study [PDF]
, 2015 Background: The emergence of new therapies for the treatment of rheumatoid arthritis (RA), the paucity of head-to-head studies, and the heterogeneous nature of responses to current biologics highlight the need for the identification of prognostic factors
Alten, Rieke +12 more
core +2 more sources
Immunomodulatory mechanisms of abatacept: A therapeutic strategy for COVID-19
Frontiers in Medicine, 2022 Coronavirus disease 2019 (COVID-19) caused by coronavirus-2 (SARS-CoV-2) infection has rapidly spread throughout the world and become a major threat to human beings. Cytokine storm is a major cause of death in severe patients.
Dinglong Yang +6 more
doaj +1 more source
Association of FCGR3A and FCGR3B haplotypes with rheumatoid arthritis and primary Sjögren's syndrome [POSTER PRESENTATION] [PDF]
, 2005 Background Rheumatoid arthritis (RA) is an autoimmune disease that is thought to arise from a complex interaction between multiple genetic factors and environmental triggers.
Barrett, J.H. +14 more
core +2 more sources
Antibody response to pneumococcal and influenza vaccination in patients with rheumatoid arthritis receiving abatacept [PDF]
, 2016 Background Patients with rheumatoid arthritis (RA), including those treated with biologics, are at increased risk of some vaccine-preventable infections. We evaluated the antibody response to standard 23-valent pneumococcal polysaccharide vaccine (PPSV23)
Alten, Rieke +6 more
core +6 more sources
Biomedicines, 2022 Objective: To prospectively evaluate the safety and efficacy profile of abatacept in patients with rheumatoid arthritis–associated interstitial lung disease (RA-ILD).
Natalia Mena-Vázquez +21 more
doaj +1 more source
Immunopathogenesis of rheumatoid arthritis [PDF]
, 2017 Rheumatoid arthritis (RA) is the most common inflammatory arthropathy. The majority of evidence, derived from genetics, tissue analyses, models, and clinical studies, points to an immune-mediated etiology associated with stromal tissue dysregulation that
Ahmed +115 more
core +1 more source
Reduced T-cell repertoire restrictions in abatacept-treated rheumatoid arthritis patients. [PDF]
, 2015 BACKGROUND: CD28(neg) T cells, which display functional characteristic of oligoclonally expanded cytotoxic memory T lymphocytes, are believed to be pathologically relevant in rheumatoid arthritis manifestation.
Airò, P +6 more
core +1 more source