Leveraging natural language processing and machine learning to identify chronic conditions from primary care electronic medical records. [PDF]
Zhang N +5 more
europepmc +1 more source
Guidelines for Initiating a Research Agenda: Topic Selection and Evidence of Impact
M. Delost, T. Nadder
semanticscholar +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
LEAPPT: Leveraging gEnerative Artificial Intelligence-Pediatric Pulmonology Training. Curriculum and content development. [PDF]
Singh AV, Khan E, Moffat M.
europepmc +1 more source
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Reply to Fuentes-Barría, H.; Aguilera-Eguía, R. Comment on "Cifuentes-Suazo et al. Dietary Counseling: An Option to Malnutrition and Masticatory Deficiency in Patients with Total Protheses? A Scoping Review. <i>Nutrients</i> 2025, <i>17</i>, 141". [PDF]
Cifuentes-Suazo G +3 more
europepmc +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Cardiovascular-kidney-metabolic syndrome: candidate subtypes and genetic risk factors. [PDF]
Donker HC +6 more
europepmc +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Comment on "Systematic Review of Continuous Glucose Monitor Accuracy in the Hypoglycemia Range for Non-Critical Care Ward Hospitalized People Living With Diabetes". [PDF]
Ahmad S, Arafat RA.
europepmc +1 more source

