Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: the Italian expanded access program [PDF]
Background: The Italian Renal Cell Cancer Early Access Program was an expanded access program that allowed access to nivolumab, for patients (pts) with metastatic renal cell carcinoma (mRCC) prior to regulatory approval.
Buti, S +22 more
core +3 more sources
The availability of Brazilian Portuguese health record text datasets for Natural Language Processing (NLP) applications is limited, especially for educational purposes.
Rildo Pinto da Silva +1 more
doaj +1 more source
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Topic modeling for entity linking using keyphrase [PDF]
This paper proposes an Entity Linking system that applies a topic modeling ranking. We apply a novel approach in order to provide new relevant elements to the model.
Mehdizadeh Naderi, Ali +2 more
core
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Syntax and semantics of the nominals mono and koto in Japanese : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Japanese at Massey University [PDF]
There is a group of words which are usually referred to as keisiki-meisi (i.e. formal nouns) in Japanese. The formal noun is defined as a noun which does not have a substantive meaning, and is not used in isolation, but requires a preceding modifier.
Murata, Masami
core
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Pattern Matching and Discourse Processing in Information Extraction from Japanese Text
Information extraction is the task of automatically picking up information of interest from an unconstrained text. Information of interest is usually extracted in two steps.
Eriguchi, Y., Hara, M., Kitani, T.
core +2 more sources

