Results 61 to 70 of about 582,977 (277)

Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: the Italian expanded access program [PDF]

open access: yes, 2019
Background: The Italian Renal Cell Cancer Early Access Program was an expanded access program that allowed access to nivolumab, for patients (pts) with metastatic renal cell carcinoma (mRCC) prior to regulatory approval.
Buti, S   +22 more
core   +3 more sources

Dataset of anonymized discharge summaries of sepsis patients from a Brazilian tertiary hospital for NLP applications.Dataverse

open access: yesData in Brief
The availability of Brazilian Portuguese health record text datasets for Natural Language Processing (NLP) applications is limited, especially for educational purposes.
Rildo Pinto da Silva   +1 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Topic modeling for entity linking using keyphrase [PDF]

open access: yes, 2014
This paper proposes an Entity Linking system that applies a topic modeling ranking. We apply a novel approach in order to provide new relevant elements to the model.
Mehdizadeh Naderi, Ali   +2 more
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Syntax and semantics of the nominals mono and koto in Japanese : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Japanese at Massey University [PDF]

open access: yes, 1999
There is a group of words which are usually referred to as keisiki-meisi (i.e. formal nouns) in Japanese. The formal noun is defined as a noun which does not have a substantive meaning, and is not used in isolation, but requires a preceding modifier.
Murata, Masami
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Pattern Matching and Discourse Processing in Information Extraction from Japanese Text

open access: yes, 1994
Information extraction is the task of automatically picking up information of interest from an unconstrained text. Information of interest is usually extracted in two steps.
Eriguchi, Y., Hara, M., Kitani, T.
core   +2 more sources

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