Results 131 to 140 of about 138,427 (307)
A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang +15 more
wiley +1 more source
Arthropodes d'importance vétérinaire pour les petits ruminants des Antilles et de Guyane [PDF]
L'inventaire des ectoparasites des petits ruminants nécessite une mise à jour. Il semble cependant qu'aux Antilles la tique Amblyomma variegatum et en Guyane les taons et les diptères myiasigènes soient les arthropodes les plus néfastes à l'élevage.
Barré, Nicolas
core
PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
Textilome de la fosse lombaire révélé par un abcès du muscle psoas gauche : rapport de cas et revue de la littérature [PDF]
Service d’Urologie-Andrologie, Hôpital Principal de Dakar, Dakar, Sénégal +17 more
openalex +1 more source
Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao +8 more
wiley +1 more source
Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu +8 more
wiley +1 more source
Antibiotic treatment durations for pyogenic liver abscesses: A systematic review. [PDF]
Curran J +4 more
europepmc +1 more source
ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu +20 more
wiley +1 more source

