Results 181 to 190 of about 4,295,538 (284)

Real-World Persistence in Adults with HIV and Mental Health or Substance Use Disorders After Restarting Antiretroviral Therapy in the United States. [PDF]

open access: yesAdv Ther
Kong AM   +9 more
europepmc   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen   +12 more
wiley   +1 more source

CCL18: a potential immunosuppressive biomarker for prognosis in ABC diffuse large B-cell lymphoma. [PDF]

open access: yesFront Immunol
Rodríguez M   +15 more
europepmc   +1 more source

Structure‐Dependent Resonant Frequency Engineering of Textile Tactile Sensors Toward Rapid and Precise Braille Recognition Surpassing Human Sensation

open access: yesAdvanced Science, EarlyView.
A resonant frequency engineering strategy is proposed to modulate the sensibility of piezoresistive textile‐based tactile sensor. It achieves simultaneous detection of static pressure and dynamic vibrations across an unprecedented bandwidth of 5–600 Hz, surpassing human sensation, therefore enables rapid and precise braille recognition.
Xianhong Zheng   +17 more
wiley   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

open access: yesAdvanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li   +9 more
wiley   +1 more source

EGaIn‐Activated Bioinspired Silk Micro/Nanofibril Eutectogels Breaking the Strength–Conductivity Trade‐Off for High‐Performance Wearable Bioelectronics

open access: yesAdvanced Science, EarlyView.
Inspired by the extracellular matrix, eutectogels are prepared by in situ deconstruction of silk fibroin into micro/nanofibrils and EGaIn‐induced polymerization. The multiscale fibril network with dynamic crosslinking achieves high strength (1.25 MPa), toughness (23.09 MJ m−3), and conductivity (1.51 S m−1), outperforming previous natural polymer ...
Haiwei Yang   +4 more
wiley   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

open access: yesAdvanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su   +18 more
wiley   +1 more source

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