Results 131 to 140 of about 13,529,064 (294)
Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity
Advanced Science, EarlyView.This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj +25 more
wiley +1 more source
Jurnal Nuansa AkademikAccurate Cost of Goods Manufactured (COGM) determination is crucial for MSMEs to maintain profitability. This study compares COGM and profit per unit between traditional and Activity-Based Costing (ABC) methods at Roti Kirana.
Astrid Faradisty +4 more
doaj +1 more source
Advanced Science, EarlyView.This work reports on epitaxially grown Hf0.52Zr0.48O2 ferroelectric memristors with high stability (high durability exceeding 108 cycles and a retention time exceeding 104 s for 16 states) and ultra‐low operating energy consumption (∼121 fJ). A memristor array‐based reservoir computing system is constructed and applied for the first time in the field ...
Ying Liu +6 more
wiley +1 more source
Advanced Science, EarlyView.Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters +12 more
wiley +1 more source
A New Method Around ABC Conjecture
, 2018 This paper is the first in a series of four devoted to the abc conjecture, the Rie-mann Hypothesis, Fermat-Wiles Theorem and its extensions, Fermat Numbers and their generalizations. We propose here a method of solving the conjecture abc based on 3 well-established properties of numbers : the sequence of successive odd numbers up to a given bound, the ...
Mukomene, Junior, Mvula, Mukomene
openaire +1 more source
, 1951 Eve Marie Martin and George Martin stand behind the counter in the ABC shop, located at 809 W. 12th St.
Douglass, Neal
core
Giant Bulk Photovoltaic Effect in Two‐Dimensional Topological Ferroelectric Semimetal
Advanced Science, EarlyView.ABSTRACT Ferroelectric (FE) metals have attracted growing interest because they combine ferroelectricity with metallic behavior and enable polarization‐controlled band topology near the Fermi level. However, the number of known ferroelectric metals is still limited.
Jianhua Wang +8 more
wiley +1 more source
A Generative Neuro‐Symbolic AI for Protein Sequence Design
Advanced Science, EarlyView.We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne +12 more
wiley +1 more source
Scalable MoS2/Si Photodiode Arrays From Roll‐to‐Roll Mechanical Exfoliation
Advanced Science, EarlyView.A dry roll‐to‐roll route transforms mechanically exfoliated MoS2 flake networks into silicon‐integrated photodiode arrays. The MoS2/Si junctions generate photovoltaic output without applied bias, allowing illuminated pixels to locate light spots and reconstruct simple images.
Yigit Sozen +2 more
wiley +1 more source
Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source