Results 91 to 100 of about 6,036 (190)
Abciximab and heparin versus bivalirudin for non-ST-elevation myocardial infarction.
The combination of glycoprotein IIb/IIIa inhibitors and heparin has not been compared with bivalirudin in studies specifically involving patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention (PCI).
Kastrati, A;Neumann, FJ;Schulz, S;Massberg, S;Byrne, RA;Ferenc, M;Laugwitz, KL;Pache, J;Ott, I;Hausleiter, J;Seyfarth, M;Gick, M;Antoniucci, D;Schömig, A;Berger, PB;Mehilli, J
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Matthew A Silva1, Jennifer L Donovan1,3, Pritesh J Gandhi2, Gregory A Volturo31Massachusetts College of Pharmacy and Health Sciences, Department of Pharmacy Practice, Worcester, MA, USA; 2Alexion Pharmaceuticals, Inc., Cheshire, CT, USA; 3UMass Memorial ...
Matthew A Silva +3 more
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Early complications may hamper efforts to hasten discharge after primary percutaneous coronary intervention (PCI) for myocardial infarction (MI). Glycoprotein IIb/IIIa inhibitors, by reducing early recurrent ischemia, may aid in these efforts.
Tcheng, James E +13 more
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Introduction: Thrombotic effects of biomaterial implants are mediated merely through activation of the platelet glycoprotein IIb-Illa (GpIIb-IIIa) receptor.
Busscher, HJ +2 more
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Acute profound thrombocytopenia without bleeding complications after re-administration of abciximab.
Abciximab (c7E3) is the Fab fragment of the chimeric (murine/human) monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor, which is the final common pathway for platelet aggregation.
Salib, H, Nguyen, N, Mascarenhas, D A
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Las Enfermedades Cardiovasculares son la principal causa de muerte en el mundo. Junto con los esfuerzos en disminuir los factores de riesgo cardiovascular, se recurre a diversos medicamentos para disminuir la morbimortalidad asociada a estas enfermedades,
Iván F PALOMO G +4 more
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Abciximab: A Pharmacoeconomic Review of its Use in Percutaneous Coronary Revascularisation
Abciximab is a monoclonal antibody fragment that inhibits platelet aggregation through antagonism of glycoprotein IIb/IIIa. The drug is used in conjunction with heparin and aspirin to prevent ischaemic complications associated with percutaneous coronary ...
Rachel H. Foster, Christopher J. Dunn
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Los inhibidores de los receptores IIb/IIIa, un nuevo grupo de antiagregantes plaquetarios, son potentes bloqueadores del receptor que media la agregación plaquetaria y de ese modo bloquean la vía final común de la formación del trombo plaquetario.
Fidel Manuel Cáceres Lóriga +1 more
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An additional mechanism of action of abciximab: dispersal of newly formed platelet aggregates
BACKGROUND: The ability of abciximab to prevent fibrinogen binding to activated platelets indicates it may also promote dissolution of platelet-rich thrombi.
Marciniak, Stanley J. Jr. +7 more
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PLATELET ANTIAGGREGANTS: MECHANISMS OF ACTION AND USE ASOCIED RISKS
Cardiovascular diseases are the main cause of death in the world. Next to efforts to reduce the cardiovascular risk factors, several drugs are resorted to decrease morbimortality associated to these diseases: antihypertensive, antidiabetic, hypolipemiant
Iván F. PALOMO G +4 more
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