Results 51 to 60 of about 5,935 (185)

Abciximab-induced delayed profound thrombocytopaenia

, 2017
No commercial use is permitted unless otherwise expressly granted. Abciximab, the first approved glycoprotein (GP IIb/IIIa) inhibitor, is being widely used during acute coronary syndromes and offers the promising approach to antithrombotic therapy.
Kailash Bajaj, Jbara, Manar, Chhabra, Lovely, Sukhdeep Bhogal, Manar Jbara, Bhogal, Sukhdeep, Bajaj, Kailash, Lovely Chhabra   +7 more
core   +1 more source

Abciximab, ticlopidine, and concomitant abciximab-ticlopidine therapy: Ex vivo platelet aggregation inhibition profiles in patients undergoing percutaneous coronary interventions

, 2000
Background We examined the ex vivo platelet aggregation profiles of patients who underwent percutaneous coronary intervention and received either abciximab, ticlopidine, or both agents.Study Design and Methods The trial was a prospective, nonrandomized ...
Maresh, K, Taylor, RJ, Kleiman, NS, Mascelli, MA, Frederick, B, Grazeiadei, N, Lance, ET, Effron, MB, Jordan, RE   +8 more
core   +1 more source

Trombose de seio dural: relato de caso Dural sinus thrombosis: case report

Arquivos de Neuro-Psiquiatria, 2006
Relata-se o caso de uma gestante de 24 anos, encaminhada ao serviço de neurologia por apresentar agitação, alucinações, confusão mental, cefaléia, perda de visão, afasia e convulsões.
Asdrubal Falavigna, João Luis Pontalti, Alisson Roberto Teles   +2 more
doaj   +1 more source

Self-Reporting Theranostic: Nano Tool for Arterial Thrombosis

Bioengineering, 2023
Arterial thrombosis (AT) originates through platelet-mediated thrombus formation in the blood vessel and can lead to heart attack, stroke, and peripheral vascular diseases.
Suryyani Deb, Mohammad Azharuddin, Sofia Ramström, Kanjaksha Ghosh, Santiswarup Singha, Thobias Romu, Hirak Kumar Patra   +6 more
doaj   +1 more source

Adjuvant antithrombotic therapy in ST-elevation myocardial infarction: A narrative review

Revista Portuguesa de Cardiologia, 2019
This article reviews the major pharmacologic features of, and clinical evidence on, adjuvant medical therapy in patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention.
Daniel Caldeira, Hélder Pereira
doaj   +1 more source

Distinct Thromboxane A₂–Dependent Pathways Regulate Arachidonic Acid–Triggered VASP Phosphorylation at Ser239 and Ser157 in Human Platelets: Real‐Time Visualization Reveals Superior Antithrombotic Efficacy by Targeting Thromboxane A₂ Signaling over Cyclooxygenase Inhibition

Journal of Cellular Physiology, Volume 241, Issue 3, March 2026.
ABSTRACT Platelets, as anucleate blood cells, play a pivotal role in the pathogenesis of cardiovascular diseases (CVDs), making antiplatelet therapy essential for preventing thrombotic events such as myocardial infarction. Thromboxane A₂ (TXA₂) is a key pro‐aggregatory mediator that drives platelet activation.
Joen‐Rong Sheu, Wei‐Chieh Huang, Chao‐Chien Chang, Chih‐Wei Hsia, Chih‐Hsuan Hsia, Thanasekaran Jayakumar, Shaw‐Min Hou   +6 more
wiley   +1 more source

Single center experience with provisional abciximab therapy in complex lower limb interventions

, 2008
BACKGROUND: Abciximab, a glycoprotein IIb/IIIa antagonist has been shown to improve patency and clinical outcome in patients undergoing endovascular recanalization of femoro-popliteal occlusions.
Diehm, Nicolas, Keo, H, Baumgartner, Iris, Diehm, N, Baumgartner, R, Husmann, Marc, Keo, Hak Hong, Husmann, M, Baumgartner, I   +8 more
core   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan, Lynn Miller, Sam Wade, Jenni Ilomäki, Dickson Lukose, Jia Rong, Geoffrey I. Webb   +6 more
wiley   +1 more source

Glycoprotein IIb/IIIa inhibitors for cardiogenic shock complicating acute myocardial infarction: a systematic review, meta-analysis, and meta-regression

Journal of Intensive Care, 2020
Background Cardiogenic shock complicates 5–10% of myocardial infarction (MI) cases. Data about the benefit of glycoprotein IIb/IIIa inhibitors (GPI) in these patients is sparse and conflicting. Methods We performed a systematic review, meta-analysis, and
Carolina Saleiro, Rogério Teixeira, Diana De Campos, João Lopes, Bárbara Oliveiros, Marco Costa, Lino Gonçalves   +6 more
doaj   +1 more source

Identification of Key Genes and Pathways Associated With Gender Differences in Pulmonary Arterial Hypertension Based on Bioinformatic Approaches

BioMed Research International, Volume 2026, Issue 1, 2026.
Pulmonary arterial hypertension (PAH) is a complex disease with multiple contributing factors. Epidemiological data showed that women are more susceptible to PAH, but they tend to have better right ventricular (RV) function and prognosis compared to men. The mechanisms behind these gender differences are not well understood.
Mohammad Panahi, Reyhaneh Kalhor, Mohammad-Hossein Mokhtarian, Fatemeh Javaheri Tehrani, Zinat Shams, Hourieh Kalhor, Hannah Wesley   +6 more
wiley   +1 more source