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Expression of miR-101-3p in Gastric Cancer and Its Effects on Invasion, Metastasis, and Angiogenesis of Gastric Cancer Cells by Targeting STC-1 Gene to Regulate PI3K/AKT Signaling Pathway

open access: yesZhongliu Fangzhi Yanjiu, 2022
Objective To explore the expression of miR-101-3p in gastric cancer and its mechanism on the invasion, metastasis, and angiogenesis of gastric cancer cells by targeting the STC-1 gene to regulate the PI3K/AKT signaling pathway.
LIU Qiang, SUN Shaoming, WANG Wenjun
doaj   +1 more source

Characterization of Specific Signatures of the Oral Cavity, Sputum, and Ileum Microbiota in Patients With Crohn’s Disease

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
BackgroundCrohn’s disease (CD) is a chronic nonspecific inflammatory bowel disease (IBD) with an increasing incidence worldwide. The etiology of CD is still obscure, but microbial dysbiosis has been recognized as an essential factor contributing to CD ...
Kai Xia   +8 more
doaj   +1 more source

Crohn’s Disease Complicated by Rare Types of Intestinal Obstruction: Two Case Reports

open access: yesFrontiers in Medicine, 2022
Intestinal obstruction is one of the most common complications of Crohn’s disease (CD), jeopardizing the quality of life of patients. Numerous factors may contribute to intestinal obstruction in CD.
Kai Xia   +9 more
doaj   +1 more source

Isobavachalcone Activates Antitumor Immunity on Orthotopic Pancreatic Cancer Model: A Screening and Validation

open access: yesFrontiers in Pharmacology, 2022
Pancreatic cancer is accompanied by poor prognosis and accounts for a significant number of deaths every year. Since Psoralea corylifolia L. (PCL) possesses a broad spectrum of bioactivities, it is commonly used in traditional Chinese medicine. The study
Xuanming Liu   +10 more
doaj   +1 more source

Abdominal skin subcutaneous fat thickness over the gestational period in Korean pregnant women: a descriptive observational study [PDF]

open access: yesKorean Journal of Women Health Nursing, 2021
Purpose Although insulin is usually injected into the abdominal subcutaneous fat, in pregnancy women tend to avoid abdominal injections due to concern about fetal damage.
Moon Sook Hwang
doaj   +1 more source

Fetal QRS Detection in Noninvasive Abdominal Electrocardiograms Using Principal Component Analysis and Discrete Wavelet Transforms with Signal Quality Estimation [PDF]

open access: yesJournal of Biomedical Physics and Engineering, 2021
Background: Fetal heart rate (FHR) extracted from abdominal electrocardiogram (ECG) is a powerful non-invasive method in appropriately assessing the fetus well-being during pregnancy.
Mohammad Javad Mollakazemi   +3 more
doaj   +1 more source

Alterations of Gut Mycobiota Profiles in Adenoma and Colorectal Cancer

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Accumulating evidence indicates that gut microbiota dysbiosis contributes to colorectal cancer and adenoma. However, a few studies revealed the altered gut mycobiota architecture in colorectal cancer.
Renyuan Gao   +11 more
doaj   +1 more source

miR-3065-3p promotes stemness and metastasis by targeting CRLF1 in colorectal cancer

open access: yesJournal of Translational Medicine, 2021
Background Colorectal cancer is one of the most common malignancy in the world. It has been reported that cancer stem cells (CSCs) serve as the primary drivers of tumorigenesis and tumor progression.
Yifan Li   +11 more
doaj   +1 more source

Hydroxytyrosol Inhibits MDSCs and Promotes M1 Macrophages in Mice With Orthotopic Pancreatic Tumor

open access: yesFrontiers in Pharmacology, 2021
The poor immunotherapy of pancreatic cancer is mainly due to its complex immunosuppressive microenvironment. The Mediterranean diet contributes to low cancer incidence. Hydroxytyrosol (HT) derived from olive oil has multiple health-promoting effects, but
Botao Wang   +12 more
doaj   +1 more source

Saikosaponin D Attenuates Pancreatic Injury Through Suppressing the Apoptosis of Acinar Cell via Modulation of the MAPK Signaling Pathway

open access: yesFrontiers in Pharmacology, 2021
Chronic pancreatitis (CP) is a progressive fibro-inflammatory syndrome. The damage of acinar cells is the main cause of inflammation and the activation of pancreatic stellate cells (PSCs), which can thereby possibly further aggravate the apoptosis of ...
Caixia Li   +7 more
doaj   +1 more source

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