Results 81 to 90 of about 172,898 (355)

Artery tertiary lymphoid organs control multi-layered territorialized atherosclerosis B cell responses in aged ApoE-/- mice [PDF]

, 2016
Objective: Explore aorta B cell immunity in aged ApoE-/- mice. Approach and Results: Transcript maps, FACS, immunofluorescence analyses, cell transfers, and Ig-ELISPOT assays showed multi-layered atherosclerosis B cell responses in artery tertiary ...
Andreas J.R. Habenicht, Changjun Yin, Christian Weber, Coleen A. McNamara, Desheng Hu, Gianluca Grassia, Kulkarni U, Li Peng, Michael Beer, Pasquale Maffia, Prasad Srikakulapu, Rudolf A. Manz, Sai Vineela Bontha, Sarajo K. Mohanta   +13 more
core   +1 more source

A Hypoxia‐Responsive Single‐Atom Sonozyme for Targeted Sonocatalytic Therapy in Alleviating Atherosclerotic Plaque

Advanced Science, EarlyView.
A tetranitrogen‐coordinated single‐atom manganese catalyst (SMC) is fabricated with outstanding sonosensitization efficiency and multi‐enzyme‐like catalytic properties. To enable better targeting of M1 macrophages, hyaluronic acid (HA) is applied to modify the surface of SMC, yielding SMC‐HA nanozymes.
Qiaofei Chen, Guotao Yuan, Zhiwen Liu, Zhengyu Cao, Li He, Ruonan Li, Tongsheng Huang, Minglong Zheng, Kexin Wen, Canxia Huang, Shuang Zhu, Pingyu Zhang, Jingfeng Wang, Yuling Zhang, Yue Pan   +14 more
wiley   +1 more source

Biodegradable Zinc‐Based Alloys for Guided Bone Regeneration Membranes: Feasibility, Current Status, and Future Prospects

Advanced Science, EarlyView.
Recent research has shown that biodegradable metals based on zinc (Zn) may be used as guided bone regeneration (GBR) membrane materials. This study examines their viability from the standpoints of material science and biology, reports on the state of research on Zn‐based GBR membranes, and suggests specific development plans based on the potential and ...
Kai Chen, Ping Li, Qiang Guan, Xuenan Gu, Li Zhao, Linjun Huang, Chenyang Huang, Yu Qin, Chunhao Yu, Ting Zhang, Hejia Li, Yongcan Huang, Yufeng Zheng   +12 more
wiley   +1 more source

ANEURYSM OF THE ABDOMINAL AORTA

Australian and New Zealand Journal of Surgery, 1958
SummaryAn account is given of the clinical features and the management of aneurysm of the ab‐dominal aorta. Rupture of the aneurysm is a common terminal event in this condition and it is desirable that operation should be undertaken before rupture occurs.
openaire   +5 more sources

Loss of Hepatic Angiotensinogen Attenuates Diastolic Dysfunction in Heart Failure with Preserved Ejection Fraction

Advanced Science, EarlyView.
Increased hepatic angiotensinogen (AGT) abundance leads to cardiac diastolic dysfunction via the AngII‐independent pathway. Liver‐derived AGT is internalized by LRP2 in cardiac endothelial cells, subsequently contributing to myocardial diastolic dysfunction by suppressing microvascular angiogenesis via inhibiting the GATA2/Pim3 pathway.
Zetao Heng, Min Hong, Zhaocai Zhang, Ximing Ye, Jianan Zhou, Wentao Wu, Jiabing Rong, Yinchuan Xu   +7 more
wiley   +1 more source

Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension

Advanced Science, EarlyView.
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi, Yang‐Xun Zhang, Jun‐Yi Chen, Sai Ma, Wei‐Xuan Xue, Wei Li, Qian‐Xiao Li, Bo Song, Ya‐Ting Li, Hong‐Yu Ma, Shu‐Tao Xie, Hong‐Zhao Li, Di‐Jun Chen, Qi‐Peng Zhang, Hui‐Jie Ma, Jian‐Jun Wang, Lei Yu, Xiao‐Yang Zhang, Jing‐Ning Zhu   +18 more
wiley   +1 more source

Takayasu's arteritis in an adult female from Cameroon: diagnosis via Doppler echocardiography [PDF]

, 2016
No abstract ...
Aminde, Leopold N, Dzudie, Anastase, Njim, Tsi, Noubiap, Jean Jacques N., Takah, Noah   +4 more
core   +1 more source

Hepatocyte‐Specific GSDMD Deficiency Aggravates Sepsis by Disrupting Non‐Canonical Secretion of Anti‐Inflammatory Factors

Advanced Science, EarlyView.
This study proposes for the first time that hepatic GSDMD plays a key protective role in sepsis. Hepatic GSDMD may release inflammatory inhibitory factors including VEGF‐B and Gremlin‐1 through pore‐forming activity to inhibit the production of inflammatory factors from macrophages, thereby alleviating the inflammatory response of septic mice ...
Yihan Qian, Bingrui Wang, Chang Yu, Yuge Zhou, Weifan Huang, Xing Rong, Yali Sang, Jiangang Song, Hailong Wu, Xiaoni Kong   +9 more
wiley   +1 more source

Wall Orientation and Shear Stress in the Lattice Boltzmann Model

, 2012
The wall shear stress is a quantity of profound importance for clinical diagnosis of artery diseases. The lattice Boltzmann is an easily parallelizable numerical method of solving the flow problems, but it suffers from errors of the velocity field near ...
Aidun, Anor, Artoli, Axner, Berger, Bernsdorf, Bonert, Boussel, Bouzidi, Boyd, Carallo, Caro, Cebral, Cecchi, Chopard, Christ, Cosgrove, Dai, d’Humieres, Gohil, Harvey, He, He, Higuera, Jou, Krüger, Krüger, Ku, Ku, Luo, Maciej Matyka, Malek, McNamara, Meyerson, Milner, Nesbitt, Nickolls, Pantos, Papaioannou, Paszkowiak, Patankar, Peng, Peters, Pohl, Pontrelli, Quarteroni, Reneman, Shaaban, Stahl, Tse, Tölke, Xian, Zbigniew Koza, Łukasz Mirosław   +53 more
core   +1 more source

Ultrasound by emergency physicians to detect abdominal aortic aneurysms: a UK case series [PDF]

, 2004
Early identification of abdominal aortic aneurysms in some patients can be difficult and the diagnosis is missed in up to 30% of patients. Ultrasound cannot be used to identify a leak, but the presence of an aneurysm in an unstable patient is ...
Brenchley, J., Lalanda, M., Sloan, J.P., Venables, H., Walker, A.   +4 more
core   +2 more sources