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The Historical Evolution of Academic Surgery at Royal Prince Alfred Hospital
ABSTRACT Surgical teaching and research at Royal Prince Alfred Hospital has evolved substantially since the hospital was opened in 1882. Economic constraints, World Wars, developments in technology, changes to healthcare policy and society's expectations have all presented opportunities and obstacles, and ultimately shaped the current practice of ...
Kilian G. M. Brown+3 more
wiley +1 more source
Immune Modulation as a Treatment for Abdominal Aortic Aneurysms [PDF]
In the United States, over 200,000 new patients are diagnosed with abdominal aortic aneurysm (AAA) each year. Consequently, over 40,000 highly morbid aortic reconstructions are performed each year to prevent aneurysm rupture, a catastrophic event ...
Murphy, Michael P., Wang, S. Keisin
core +1 more source
Metformin and Abdominal Aortic Aneurysm [PDF]
Recently published data from a number of sources appear to suggest that the oral hypoglycaemic agent metformin may prevent abdominal aortic aneurysm (AAA) development, attenuate growth, and perhaps even prevent rupture. Previous studies have hinted that hypoglycaemic agents might reduce AAA expansion.1 The latest data, specific to metformin are ...
openaire +5 more sources
Summary The JAK2V617F mutation is associated with increased cardiovascular risk, including ischaemic stroke. This study investigates the prevalence of additional mutations in ischaemic cerebrovascular patients with and without JAK2V617F to better understand the mechanisms contributing to thrombotic risk.
Marie Hvelplund Kristiansen+5 more
wiley +1 more source
Abstract Background and Purpose Our previous study reported that fructose intake increased systemic blood pressure and reduced nitric oxide (NO) in the nucleus tractus solitarius (NTS) due to oxidative stress and neuroinflammation. However, it remains unclear how reactive oxygen species (ROS) reduce NO and how this process impacts neuroinflammation in ...
Yu‐Te Lin+6 more
wiley +1 more source
Background Acute pancreatitis caused by surgical procedures may occur less frequently in surgeries for aortic aneurysm involving the abdominal branch. However, in such cases, the associated mortality rate increases significantly.
Kazuhiro Yamazaki+6 more
doaj +1 more source
Consecutive failing proximal landing zones
We report the case of a 77-year-old man who presented with successive aortic aneurysms during a 12-year period. He was first treated in 2006 for an abdominal aortic aneurysm with a bifurcated endograft, then in 2016 for a tender type IV thoracoabdominal ...
Côme Bosse, MD+4 more
doaj +1 more source
Statin intensity and postoperative mortality following open repair of intact abdominal aortic aneurysm. [PDF]
BackgroundThere is a lack of evidence for the association between intensive statin therapy and outcomes following vascular surgery. The aim of this study was to evaluate the association between perioperative statin intensity and in-hospital mortality ...
Alshaikh, HN+4 more
core
MFG‐E8 promotes oxidative stress by upregulating NOX4 and activating the MAPK pathway, which increases ROS production and affects vascular smooth muscle cell (VSMC) apoptosis, thereby driving the progression of abdominal aortic aneurysm (AAA). Resveratrol can inhibit the expression and function of MFG‐E8, reduce ROS generation, and lower the incidence ...
Jie Xiao+6 more
wiley +1 more source
Idiopathic Retroperitoneal Fibrosis Presenting with Hypertension and Acute Renal Failure
Abdominal aortic aneurysm can rarely cause retroperitoneal fibrosis secondary to the leakage of inflammatory cells from aortic plaques to the retroperitoneal area.
Engin Onan+5 more
doaj +1 more source