Results 111 to 120 of about 108,365 (307)

The Historical Evolution of Academic Surgery at Royal Prince Alfred Hospital

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Surgical teaching and research at Royal Prince Alfred Hospital has evolved substantially since the hospital was opened in 1882. Economic constraints, World Wars, developments in technology, changes to healthcare policy and society's expectations have all presented opportunities and obstacles, and ultimately shaped the current practice of ...
Kilian G. M. Brown   +3 more
wiley   +1 more source

Immune Modulation as a Treatment for Abdominal Aortic Aneurysms [PDF]

open access: yes, 2018
In the United States, over 200,000 new patients are diagnosed with abdominal aortic aneurysm (AAA) each year. Consequently, over 40,000 highly morbid aortic reconstructions are performed each year to prevent aneurysm rupture, a catastrophic event ...
Murphy, Michael P., Wang, S. Keisin
core   +1 more source

Metformin and Abdominal Aortic Aneurysm [PDF]

open access: yesEuropean Journal of Vascular and Endovascular Surgery, 2017
Recently published data from a number of sources appear to suggest that the oral hypoglycaemic agent metformin may prevent abdominal aortic aneurysm (AAA) development, attenuate growth, and perhaps even prevent rupture. Previous studies have hinted that hypoglycaemic agents might reduce AAA expansion.1 The latest data, specific to metformin are ...
openaire   +5 more sources

Prevalence and impact of additional CHIP mutations in JAK2V617F‐positive ischaemic cerebrovascular patients

open access: yesBritish Journal of Haematology, EarlyView.
Summary The JAK2V617F mutation is associated with increased cardiovascular risk, including ischaemic stroke. This study investigates the prevalence of additional mutations in ischaemic cerebrovascular patients with and without JAK2V617F to better understand the mechanisms contributing to thrombotic risk.
Marie Hvelplund Kristiansen   +5 more
wiley   +1 more source

Targeting acetylated high mobility group box 1 protein (HMGB1) and toll‐like receptor (TLR4) interaction to alleviate hypertension and neuroinflammation in fructose‐fed rats

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Our previous study reported that fructose intake increased systemic blood pressure and reduced nitric oxide (NO) in the nucleus tractus solitarius (NTS) due to oxidative stress and neuroinflammation. However, it remains unclear how reactive oxygen species (ROS) reduce NO and how this process impacts neuroinflammation in ...
Yu‐Te Lin   +6 more
wiley   +1 more source

Two cases of pararenal artery aortic aneurysm treatment after pancreaticoduodenectomy and abdominal aortic aneurysm stent grafting

open access: yesSurgical Case Reports
Background Acute pancreatitis caused by surgical procedures may occur less frequently in surgeries for aortic aneurysm involving the abdominal branch. However, in such cases, the associated mortality rate increases significantly.
Kazuhiro Yamazaki   +6 more
doaj   +1 more source

Consecutive failing proximal landing zones

open access: yesJournal of Vascular Surgery Cases and Innovative Techniques, 2019
We report the case of a 77-year-old man who presented with successive aortic aneurysms during a 12-year period. He was first treated in 2006 for an abdominal aortic aneurysm with a bifurcated endograft, then in 2016 for a tender type IV thoracoabdominal ...
Côme Bosse, MD   +4 more
doaj   +1 more source

Statin intensity and postoperative mortality following open repair of intact abdominal aortic aneurysm. [PDF]

open access: yes, 2018
BackgroundThere is a lack of evidence for the association between intensive statin therapy and outcomes following vascular surgery. The aim of this study was to evaluate the association between perioperative statin intensity and in-hospital mortality ...
Alshaikh, HN   +4 more
core  

MFG‐E8 Accelerates Abdominal Aortic Aneurysm Formation by Enhancing ERK MAPK/NOX4 Axis‐Associated Oxidative Stress

open access: yesCell Proliferation, EarlyView.
MFG‐E8 promotes oxidative stress by upregulating NOX4 and activating the MAPK pathway, which increases ROS production and affects vascular smooth muscle cell (VSMC) apoptosis, thereby driving the progression of abdominal aortic aneurysm (AAA). Resveratrol can inhibit the expression and function of MFG‐E8, reduce ROS generation, and lower the incidence ...
Jie Xiao   +6 more
wiley   +1 more source

Idiopathic Retroperitoneal Fibrosis Presenting with Hypertension and Acute Renal Failure

open access: yesİstanbul Medical Journal, 2017
Abdominal aortic aneurysm can rarely cause retroperitoneal fibrosis secondary to the leakage of inflammatory cells from aortic plaques to the retroperitoneal area.
Engin Onan   +5 more
doaj   +1 more source

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