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Synergistic elastase and papain injury drives abdominal aortic aneurysm formation and rupture in mice. [PDF]

open access: yesCommun Med (Lond)
Elizondo-Benedetto S   +5 more
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Abdominal aortic aneurysms

Progress in Cardiovascular Diseases, 2021
Abdominal aortic aneurysms (AAA) are prevalent among older adults and can cause significant morbidity and mortality if not addressed in a timely fashion. Their etiology remains the topic of continued investigation. Known causes include trauma, infection, and inflammatory disorders.
John, Anagnostakos, Brajesh K, Lal
openaire   +4 more sources

Abdominal aortic aneurysms

Nature Reviews Disease Primers, 2018
An abdominal aortic aneurysm (AAA) is a localized dilatation of the infrarenal aorta. AAA is a multifactorial disease, and genetic and environmental factors play a part; smoking, male sex and a positive family history are the most important risk factors, and AAA is most common in men >65 years of age.
SAKALIHASAN, Natzi   +8 more
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Abdominal aortic aneurysms

Current Treatment Options in Cardiovascular Medicine, 1999
The mortality rate after the rupture of an abdominal aortic aneurysm is 80% to 90%; therefore, the main goal of treatment is to prevent rupture. Patients with abdominal aortic aneurysms smaller than 5 cm in diameter should be managed conservatively under close surveillance with either computed tomography or sonography every 3 to 12 months.
, Ohki, , Veith
openaire   +2 more sources

Epidemiology of abdominal aortic aneurysms

Seminars in Vascular Surgery, 2021
Abdominal aortic aneurysm (AAA) disease remains a major source of morbidity in developed countries and can progress to life-threatening rupture if left untreated, with exceedingly high mortality. The goal of AAA management is to identify and electively repair AAAs before rupture.
Christina L, Marcaccio   +1 more
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Abdominal Aortic Aneurysm

The Journal of Cardiovascular Nursing, 2001
Abdominal aortic aneurysm is a chronic dilation of the aorta with a natural history toward enlargement and rupture. Its pathogenesis is believed to be multifactorial and complex. Clinical presentation may be asymptomatic, symptomatic, or as rupture.
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Abdominal aortic aneurysms

Current Opinion in Cardiology, 1994
The management of abdominal aortic aneurysms has undergone tremendous evolution during the past three decades, resulting in significant advances in our ability to diagnose and safety treat patients with aneurysms. Over the past several years, most research interest has been focused on the etiology of aneurysmal disease, new imaging techniques, cardiac ...
M, Belkin   +2 more
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