Results 71 to 80 of about 108,365 (307)

Mechanosignals in abdominal aortic aneurysms

Frontiers in Cardiovascular Medicine, 2023
Cumulative evidence has shown that mechanical and frictional forces exert distinct effects in the multi-cellular aortic layers and play a significant role in the development of abdominal aortic aneurysms (AAA). These mechanical cues collectively trigger signaling cascades relying on mechanosensory cellular hubs that regulate vascular remodeling ...
Christiana Lowis, Christiana Lowis, Aurellia Ramara Winaya, Aurellia Ramara Winaya, Puja Kumari, Puja Kumari, Cristobal F. Rivera, Cristobal F. Rivera, John Vlahos, John Vlahos, Rio Hermantara, Muhammad Yogi Pratama, Muhammad Yogi Pratama, Bhama Ramkhelawon, Bhama Ramkhelawon   +14 more
openaire   +3 more sources

Ocular Findings as the Most Striking Manifestation of a SMAD3 Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Loeys‐Dietz syndrome (LDS) is a heritable connective tissue disorder with variable expressivity. It is a multisystemic condition mainly characterized by a propensity for arterial aneurysms and dissections, skeletal manifestations, hypertelorism, bifid uvula, craniosynostosis, and cutaneous features.
Noémie Villeneuve‐Cloutier, Christie A Boswell‐Patterson, Lucas Bronicki, Krista M. Vincent, Kalin Wilk, Andrea C. Yu, Gail E. Graham, Julie Richer   +7 more
wiley   +1 more source

Cycloastragenol Inhibits Experimental Abdominal Aortic Aneurysm Progression

Biomedicines, 2022
The pathogenesis of abdominal aortic aneurysm involves vascular inflammation and elastin degradation. Astragalusradix contains cycloastragenol, which is known to be anti-inflammatory and to protect against elastin degradation.
Leander Gaarde Melin, Julie Husted Dall, Jes S. Lindholt, Lasse B. Steffensen, Hans Christian Beck, Sophie L. Elkrog, Pernille D. Clausen, Lars Melholt Rasmussen, Jane Stubbe   +8 more
doaj   +1 more source

Computational fluid dynamicaccuracy in mimicking changes in blood hemodynamics in patients with acute type IIIb aortic dissection treated with TEVAR [PDF]

, 2018
Background: We aimed to verify the accuracy of the Computational Fluid Dynamics (CFD) algorithm for blood flow reconstruction for type IIIb aortic dissection (TBAD) before and after thoracic endovascular aortic repair (TEVAR).
Domenig, Christoph, Huk, Ihor, Nanobachvili, Josif, Neumayer, Christoph, Piechota-Polańczyk, Aleksandra, Polanczyk, Andrzej   +5 more
core   +1 more source

SOX6 enhances vascular smooth muscle cell phenotypic switching and elevates blood pressure by activating autophagy

Animal Models and Experimental Medicine, EarlyView.
Sox6 expression is elevated in hypertensive conditions and promotes vascular smooth muscle cell phenotypic switching through autophagy activation. Using gain‐ and loss‐of‐function approaches both in vitro and in vivo, we demonstrate that Sox6 regulates blood pressure and vascular remodeling, highlighting its potential as a novel therapeutic target for ...
Qianhui Ling, Xilan Dong, Liyan Mao, Chengjun Huang, Linjing Cong, Haizeng Zhang, Jun Cai, Zhenzhen Chen   +7 more
wiley   +1 more source

Genome‐wide DNA methylation study reveals specific signatures in the affected arterial tissue of giant cell arteritis patients

Arthritis &Rheumatology, Accepted Article.
Objectives Giant cell arteritis (GCA) is a large‐vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by identifying specific DNA methylation signatures in the arterial tissue of patients with this vasculitis.
Gonzalo Borrego‐Yaniz, Ana Márquez, Elkyn Estupiñán‐Moreno, Laura C. Terrón‐Camero, Miguel A. González‐Gay, Santos Castañeda, Giuliana Guggino, David Saadoun, Pietro Lio, Simona Fontana, Martina Bonacini, Alessandro Rossi, Alberto Cavazza, Francesco Muratore, Carlo Salvarani, Nicolo Pipitone, Javier Martin, Stefania Croci, Lourdes Ortiz‐Fernández   +18 more
wiley   +1 more source

Chronic contained rupture of abdominal aortic aneurism complicated with aortic occlusion: a case report

Surgical Case Reports, 2019
Background Chronic contained rupture is a subtype of an abdominal aortic aneurysm rupture. Its diagnosis is sometimes difficult due to lack of typical symptoms.
Azuma Tabayashi, Takeshi Kamada, Akihiko Abiko, Ryoichi Tanaka, Hajime Kin   +4 more
doaj   +1 more source

Acute dissection of the coexistent abdominal aortic aneurysm

Annals of Vascular Surgery - Brief Reports and Innovations, 2022
We present a 76-year-old female who complained about severe back pain. Contrast-enhanced computed tomography revealed a 5-cm abdominal aortic aneurysm with a large primary entry causing retrograde type B aortic dissection limited to the abdominal lesion.
Naoto Fukunaga, Akio Shimoji, Toshi Maeda, Otohime Mori, Kosuke Yoshizawa, Nobushige Tamura   +5 more
doaj   +1 more source

Experience of a tutor centric model for sonography training of emergency department registrars in an Australian urban emergency department 2009–2012 [PDF]

, 2015
Purpose: To assess the impact of a regular sonographer proctored training program for emergency medicine trainees in the use of Emergency Department bedside ultrasound Methods: Emergency Department (ED) Registrars in the Swan District Hospital ED were ...
Fear, Mark, Hird, Kathryn, Sweetman, Greg   +2 more
core   +2 more sources

Screening for abdominal aortic aneurysms [PDF]

European Journal of Vascular and Endovascular Surgery, 2003
AbstractEur J Vasc Endovasc Surg 25, 377-379 (2003)
openaire   +3 more sources