Results 81 to 90 of about 165,409 (275)

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

open access: yesMed Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang   +22 more
wiley   +1 more source

Blood pressure, hypertension, and the risk of aortic aneurysm in the UK Biobank

open access: yesBMC Cardiovascular Disorders
Background Although an association between elevated blood pressure and risk of aortic aneurysm is established, few studies have investigated the association with aortic aneurysm subtypes.
Rida E.Z. Naqvi   +6 more
doaj   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

Abdominal aortic aneurysm and cardiometabolic traits share strong genetic susceptibility to lipid metabolism and inflammation

open access: yesNature Communications
Abdominal aortic aneurysm has a high heritability and often co-occurs with other cardiometabolic disorders, suggesting shared genetic susceptibility.
Shufen Zheng   +2 more
doaj   +1 more source

Longest survivor of pulmonary atresia with ventricular septal defect without surgical intervention

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 1499-1507, April 2025.
Sang Zhou   +5 more
wiley   +1 more source

The Epidemiology of Aortic Aneurysms: Global and Regional Trends Between 1990 and 2021

open access: yesMedicine Advances, EarlyView.
This study presents the first comprehensive global analysis of the burden and inequality of aortic aneurysm (AA) using GBD 2021 data across 204 countries and territories. While the overall global burden of AA has declined over the past three decades, our findings reveal a concerning rise in AA‐related mortality and disability‐adjusted life years (DALYs)
Jiarui Zhang   +7 more
wiley   +1 more source

Meta‐analysis of the current prevalence of screen‐detected abdominal aortic aneurysm in women

open access: yesBritish Journal of Surgery, 2016
Although women represent an increasing proportion of those presenting with abdominal aortic aneurysm (AAA) rupture, the current prevalence of AAA in women is unknown. The contemporary population prevalence of screen‐detected AAA in women was investigated
P. Ulug   +12 more
semanticscholar   +1 more source

Dasatinib Produces Lengthy Remissions of Extramedullary Leukemia: A Retrospective Observational Study

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Since 2004, patients receiving imatinib with relapse in non‐marrow sites were given dasatinib to preserve control of leukemic marrow. Remissions in CNS and other organs began to be reported and are continuously observed to present. With resistance to one BCR::ABL1 tyrosine kinase inhibitor and sensitivity to a dual BCR::ABL1/SRC inhibitor ...
I. Cunningham   +4 more
wiley   +1 more source

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