Results 71 to 80 of about 905,782 (286)

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

The severe abdominal effusion in a camel [PDF]

Eurasian Journal of Veterinary Sciences
In this case report was presented a 15 years old male dromedary camel with severe abdominal effusion. The exploratory laparotomy was performed through the left paralumbar lossae.
Yılmaz Koç, Fahrettin Alkan, Alparslan Coşkun   +2 more
doaj  

Engineering Morphological Anisotropy to Control the In Vivo Transport Dynamics, Clearance, and Biodistribution of Silica Nanocarriers

Advanced Science, EarlyView.
Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li, Yingjie Yu, Tianchang He, Xiaoyan Fang, Wenhua Yang, Luying Zhou, Hao Fan, Guimei Lin, Daniel Crespy, Katharina Landfester, Junfeng Zhang, Shuai Jiang   +11 more
wiley   +1 more source

ASPIRATION BIOPSY PECULIARITIES IN CASE OF INACCESIBLE TUMORS OF ABDOMINAL CAVITY ORGANS [PDF]

Саратовский научно-медицинский журнал, 2008
In case of three-dimensional visualization the choice ofparacentetic trajectory for access to organs and neoplasms of abdominalcavityand retroperitoneal area can be improved in a great degree. Three-dimensional visualization ofparacentetic trajectory and
S.Sh. Dagayev, S.A. Panfilov, F.Z. Chanyshev, V.S. Khabitsov   +3 more
doaj  

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Diagnostic capabilities of computed tomography in the pathology of the abdominal cavity in small animals

RUDN Journal of Agronomy and Animal Industries, 2010
Computed tomography (CT) provides highly informative results as a diagnostic test used to diagnose diseases of the abdominal cavity. Correct animal's positioning and a scan examination protocol allow to obtain a number of high-quality CT images.
I V Shurov, I E Ludin
doaj  

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

Advanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang, Liechao Yu, Wanchang Zhang, Gary Wessel, Ruiyi Chen, Weihua Hu, Dongdong Xu   +6 more
wiley   +1 more source

Cavity flow noise predictions

, 2007
The near and far pressure fields of three-dimensional turbulent cavity flow are studied by time-accurate simulations coupled with aeroacoustic predictions.
Zhang, Xin, Chen, Xiaoxian, Xin Zhang, Xiaoxian Chen, Sandham, Neil D., Neil D. S   +5 more
core   +1 more source

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

Advanced Science, EarlyView.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang, Yangfan Huo, Jin Liu, Sida Liu, Minghai Ma, Hao Guo, Yuanquan Zhang, Xing Li, Xiao Liang, Jiawei Xiu, Ying Sun, Lijun Huang, Xiaolong Yan, Weiwei Wu, Lei Wang   +14 more
wiley   +1 more source

A case of extraumbilical ectopia hepatica in a lamb [PDF]

Eurasian Journal of Veterinary Sciences
In this study, the extraumbilical ectopia hepatice in a three days old, female. 4 kg weight. Akkaraman breed lamb was described. The abdominal wall at the umbilicus was widened and abdominal cavity was observed for any ab-normahes and refuse.
Yılmaz Koç, Fahrettin Alkan
doaj