Results 81 to 90 of about 1,501,388 (294)

Association of DPP4 with esophageal stricture progression and the Hippo‐YAP pathway

Animal Models and Experimental Medicine, EarlyView.
This study establishes a comprehensive translational platform for esophageal stricture (ES) research by integrating a novel rat model with clinically relevant porcine validation. This study identifies DPP4 as a gene of interest associated with ES following endoscopic submucosal dissection, demonstrating that prophylactic DPP4 inhibition attenuates ...
Rui Wu, Chen Wang, Hui‐Min Tao, Jin Huang, Wei‐Qin Li, Zhi‐Ning Fan   +5 more
wiley   +1 more source

Waist circumference and abdominal volume index are the strongest anthropometric discriminators of metabolic syndrome in Spanish adolescents

European Journal of Clinical Investigation, 2018
Waist circumference has been suggested as predictor for metabolic syndrome (MetS) in adolescents but it has not been compared with newly proposed anthropometric indexes.
J. S. Perona, Jacqueline Schmidt Río-Valle, R. Ramírez-Vélez, M. Correa-Rodríguez, Ángel Fernández-Aparicio, E. González-Jiménez   +5 more
semanticscholar   +1 more source

Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies [PDF]

, 2011
BACKGROUND: Guidelines differ about the value of assessment of adiposity measures for cardiovascular disease risk prediction when information is available for other risk factors. We studied the separate and combined associations of body-mass index (BMI),
Nordestgaard, Borge G., Stehouwer, Coen; id_orcid, Kaptoge, S., Danesh, J, Wood, Angela M., Thompson, Alex, Sattar, N, Thompson, A, Wormser, D, Emerging Risk Factors Collaboration, Risérus, Ulf,, Salomma, V, Sarwar, N, Danesh, J., Wood, Angela M, Pennells, L, Ärnlöv, Johan,, Woodward, M., Salomaa, Veikko, Sundström, Johan,, Thompson, S.G., Kaptoge, S, Tybjærg-Hansen, Anne, Wormser, D., Ridker, P, Thompson, Simon G, null The Emerging Risk Factors Collaboration, Woodward, Mark, Kizer, Jorge R, Frikke-Schmidt, Ruth, Nordestgaard, BG, Kaptoge, Stephen, Salomaa, V, Lawlor, DA, Eriksson, Henry,, Sarwar, Nadeem, Wood, AM, Kizer, Jorge R., Pennells, Lisa, Stevens, June, Pennells, L., Whitlock, G, Salomaa, V., Nordestgaard, B.G., Collins, Rory, Ridker, Paul, Thompson, A., Lawlor, D.A., Woodward, M, Collins, R, Kizer, J.R., Sattar, N., Lawlor, Debbie A, Sarwar, N., Ingelsson, Erik,, Davey Smith, George, Danesh, John, Stehouwer, Coen, Ridker, P., The Emerging Risk Factors Collaboration,, Di Angelantonio, Emanuele, Wood, A.M., Whitlock, G., Di Angelantonio, E., Sattar, Naveed, Lawlor, Debbie A., Collins, R., Di Angelantonio, E, Kizer, JR, Whitlock, Gary, Thompson, SG, Nordestgaard, Børge G, Stevens, J, Wormser, David, Stevens, J., Thompson, Simon G., Di Angeloantonio, Emanuele, Emerging Risk Factors Collaboration (Döring, A. ; Meisinger, C.)   +77 more
core   +1 more source

1,2‐propanediol reformulation improves tribromoethanol safety and reveals pontine GABRA1 enrichment as a candidate mechanistic correlate of anesthesia

Animal Models and Experimental Medicine, EarlyView.
This study develops a reformulated tribromoethanol (TBE) anesthetic using 1,2‐propanediol as a solvent to overcome solvent‐related toxicity. The novel formulation demonstrates, cardiovascular stability, and survival in prolonged protocols. It provides potent, dose‐dependent anesthesia without strain or sex differences.
Xia Li, Yanming Chen, Xinyi Xiao, Guoheng Xu   +3 more
wiley   +1 more source

Silk Fibroin for Cardiovascular Medical Devices: Review of Material Properties, Applications, and Clinical Potential

Advanced NanoBiomed Research, EarlyView.
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab, Matt Govendir, Kristina Andelovic, Zachary Och, Fatemeh Karimi, Munira Xaymardan, Tomasz Jungst, Jelena Rnjak‐Kovacina, Nona Farbehi   +8 more
wiley   +1 more source

COPD in England: a comparison of expected, model-based prevalence and observed prevalence from general practice data

, 2010
BACKGROUND: Primary care data show that 765 000 people in England have a general practice (GP) diagnosis of chronic obstructive pulmonary disease (COPD).
Majeed, Azeem, L. Nacul, Michael Soljak, Nicholas S Hopkinson, E. Samarasundera, Luis Nacul, A. Majeed, Edgar Samarasundera, Samarasundera, Edgar, Hopkinson, Nicholas S., Nacul, Luis, Hannah Walford, Walford, Hannah, Soljak, Michael, Lacerda, Eliana, Tejal Indulkar, M. Soljak, J. Flowers, Flowers, Julian, N. S. Hopkinson, Hopkinson, Nicholas S, Indulkar, Tejal, T. Indulkar, Julian Flowers, Azeem Majeed, H. Walford, Eliana Lacerda, E. Lacerda   +27 more
core   +1 more source

Evaluation of Bioelectrical Impedance Analysis for Identifying Overweight Individuals at Increased Cardiometabolic Risk:A Cross-Sectional Study [PDF]

, 2014
OBJECTIVE: To investigate whether bioelectrical impedance analysis could be used to identify overweight individuals at increased cardiometabolic risk, defined as the presence of metabolic syndrome and/or diabetes.DESIGN AND METHODS: Cross-sectional study
Lamb Maxine J. E., Christopher D Byrne, Wilson, J.F., Lamb, M.J.E., Wild, S.H., Lamb, Maxine J E, Byrne, Christopher D, Wild, Sarah H; id_orcid, Wilson James F., Byrne Christopher D., Sarah H Wild, James F Wilson, Wild Sarah H., Wilson, James F; id_orcid, Byrne, Christopher D., Maxine J E Lamb   +15 more
core   +1 more source

Over the edge: Empirical evidence for the cliff‐edge model of obstetric selection

The Anatomical Record, EarlyView.
Abstract The cliff‐edge model of obstetric selection maintains that larger neonates and smaller birth canals confer a positive selective advantage until labor becomes obstructed and vaginal delivery is no longer possible, eliciting an abrupt reduction in fitness.
Laura M. Watson, Pierre Frémondière, Kaspar Staub, Philipp Mitteroecker, Barbara Fischer, Martin Haeusler, Nicole M. Webb   +6 more
wiley   +1 more source

Effect of Abdominal Circumference and Fetal Weight on Supine Hypotension during C-Section under Spinal Anesthesia

Pakistan Journal of Medical Research
Background: Spinal anesthesia is the safest and most popular technique used for cesarean section worldwide. Certain maternal and fetal conditions such as increased maternal abdominal circumference and fetal weight can have profound effect on degree of ...
Hubba Ahmed, Zaira Batool, Shaista Rashid, Ashok Perchani, Farjad Sultan   +4 more
doaj   +4 more sources

The Finnish Diabetes Risk Score (FINDRISC) and increased body weight

Journal of Medical Science, 2016
Introduction. The Finnish Diabetes Risk Score (FINDRISC) assesses the 10-year type 2 diabetes risk in adults by identifying individuals with overweight or obesity, inadequate physical activity, poor nutrition, or a family or personal history of ...
Joanna Pekar, Rafał Mazur, Małgorzata Kozilewicz, Aleksandra Jóźwiak, Anna Olszewska, Katarzyna Skórzyńska-Dziduszko   +5 more
doaj   +1 more source