Results 131 to 140 of about 1,607,397 (243)

Asparagine Synthetase Deficiency: Neuropathological Evidence of Disrupted Cortical Development

open access: yesJIMD Reports, Volume 67, Issue 5, September 2026.
ABSTRACT Asparagine synthetase deficiency (ASNSD) is a rare metabolic disease causing congenital microcephaly, severe developmental delay, and spastic quadriplegia. Although the central nervous system is severely affected, other organ systems appear unaffected by asparagine deficiency.
Mihaela Bobić   +15 more
wiley   +1 more source

A Novel Preclinical Rat Model of Acute Compartment Syndrome

open access: yesJournal of Orthopaedic Research, Volume 44, Issue 9, September 2026.
ABSTRACT Acute compartment syndrome (ACS) is common in trauma, challenging early diagnosis and treatment. An accurate ACS model is vital for its management. Most prior animal models have induced intrafascial hypertension by exogenous interventions, focusing on the study of secondary injury post‐ACS formation.
Sishu Guan   +6 more
wiley   +1 more source

Contribution of tissue oximetry to the assessment of renal dysfunction in abdominal compartment syndrome: an experimental canine study. [PDF]

open access: yesFront Surg
Nalbanti V   +11 more
europepmc   +1 more source

Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait   +5 more
wiley   +1 more source

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu   +6 more
wiley   +1 more source

Abdominal compartment syndrome in critically ill patients. [PDF]

open access: yesAcute Crit Care, 2023
Jang H   +6 more
europepmc   +1 more source

Migraine: Epidemiology, Risk Factors, Pathophysiology, and Treatment

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Migraine is a highly prevalent, female‐predominant, and disabling brain disorder shaped by genetic susceptibility, hormonal influences, modifiable attack factors, and comorbidity‐related progression. This review integrates current evidence on migraine epidemiology, phase‐specific neurovascular and neuroglial mechanisms, including CGRP signaling and ...
Weiwei Lu   +9 more
wiley   +1 more source

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