Results 111 to 120 of about 2,600,985 (388)

Splenic Trauma: should we treat differently? [PDF]

, 2003
A 36 year old male was admitted to Accident and Emergency Department following a motor vehicle accident. Clinical examination revealed a haemodynamically stable patient. Abdominal examination showed tenderness in right upper quadrant.
Andrejevic, Predrag, LaFerla, Godfrey
core  

Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition

Advanced Science, EarlyView.
Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu, Zhihuang Zheng, Marleen Silke Oswald, Guozhe Cheng, Jun Liu, Qidi Zhai, Ute Kruegel, Michael Schaefer, Holger Gerhardt, Nicole Endlich, Maik Gollasch, Stefan Simm, Dmitry Tsvetkov   +12 more
wiley   +1 more source

Is whole-body trauma MDCT justified in patients in good clinical condition but with dangerous trauma mechanism? [PDF]

, 2009
Background: To assess whether whole body MDCT is justified in patients in good clinical condition yet with dangerous trauma mechanism. Material/Methods: The study included 81 patients who were examined between January and July 2008 with wholebody trauma ...
Blaz, Marcin, Golebiowski, Marek, Palczewski, Piotr, Swiatkowski, Jan, Szeszkowski, Wojciech, Wisniewska, Malgorzata   +5 more
core  

Inhibition and Rescue of Hyperglycemia‐Induced Cellular Senescence by Mitochondrial Transfer from Enucleated Mesenchymal Stem Cell‐Derived Microvesicles for Chronic Wound Healing

Advanced Science, EarlyView.
This study develops enucleated MSC‐derived microvesicles (Mito@euMVs) to deliver functional mitochondria for optimizing wound repair. By efficiently encapsulating mitochondria, Mito@euMVs rejuvenate hyperglycemia‐induced senescent fibroblasts and HUVECs. Using PVA microneedle patches, the therapeutic efficacy of Mito@euMVs is validated in diabetic rats
Zixuan Dong, Xiaobing Liu, Shichun Li, Xiaoling Fu   +3 more
wiley   +1 more source

Trauma hepático: epidemiologia de cinco anos em um serviço de emergência

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: analisar características epidemiológicas relacionadas ao trauma hepático e fazer breve revisão das modalidades diagnósticas e de tratamento.
Carla Martinez Menini Stalhschmidt, Beatriz Formighieri, Débora Majszak Marcon, Aline Luri Takejima, Luis Guilherme Sanches Soares   +4 more
doaj   +1 more source

Complex vascular injury in a case of multiple gunshot wounds in a combat zone

Indian Journal of Vascular and Endovascular Surgery, 2018
Abdominal vascular injuries are the most common cause of early death after penetrating abdominal trauma if especially associated with a chest injury and fracture of long bones.
Vivek Agrawal, Dhananjay Singh, Sandeep Mehrotra, Varinder Bedi   +3 more
doaj   +1 more source

Invasive monitoring of the clinical effects of high intra-abdominal pressure for insertion of the first trocar. [PDF]

, 2011
Background: To analyze the effects of transitory, high intra-abdominal pressure on clinical, hemodynamic, blood gas and metabolic parameters. Methods: Sixty-seven laparoscopic patients were divided into groups P12 (n = 30, maximum ...
Afonso C. C. G. Machado, Bianca Marigliani, Fernanda A. B. Gama, Glicia C. Azevedo, Gustavo P. S. Miguel, Joao-Luiz Azevedo, José, Linda Bernardes, Octavio H. M. Hypolito, Otavio C. Azevedo, Otavio M. Becker Junior, Susana A. Miyahira   +11 more
core   +1 more source

Leptin Aggravates Thoracic Aortic Dissection Through Impairment of Energy Metabolism in Nrip2+ Smooth Muscle Cells

Advanced Science, EarlyView.
Epidemiological data confirm obesity elevates thoracic aortic dissection (TAD) risk. Patient analyses implicate hyperleptinemia, where leptin binding to vascular smooth muscle cell (VSMC) receptors triggers Socs3‐mediated suppression of Stat5a transcriptional activity.
Ling Chen, Yujie Zhu, Xi Yang, JiangBin Wu, Keyuan Chen, Wuqing Huang, Lu Fang, Qi Zhang, Jie Chen, Jianing Gao, Huanhuan Cao, Meifang Wu, Zhihuang Qiu, Yuling Zhang, Yue Shen, Qiuyu Huang, Zhiyong Lin, Lemin Zheng, Liangwan Chen   +18 more
wiley   +1 more source

Gunshot Abdominal Injuries: A Report of Two Cases and a Review of the Literature. [PDF]

Medicina (Kaunas), 2023
Elek Z, Igrutinovic G, Grujic B, Djordjevic I, Konstantinovic S.   +4 more
europepmc   +1 more source

Dopamine D1 Receptor Contributes to Glucocorticoid‐Associated Osteonecrosis of Femoral Head Protection Through the ATF3/CHOP Axis to Inhibit Osteoblastic Apoptosis

Advanced Science, EarlyView.
This work identifies a novel mechanism by which dopamine D1 receptor (DRD1) contributes to the pathogenesis of glucocorticoid (GC)‐associated osteonecrosis of the femoral head (ONFH) through the regulation of osteoblastic apoptosis, indicating that DRD1 serves as a critical mediator of the crosstalk between the nervous and skeletal systems.
Kai Zheng, Wenming Li, Tianhao Wang, Gaoran Ge, Wei Zhang, Yi Qin, Wenhao Li, Zebin Wu, Zhen Wang, Gang Rui, Yaozeng Xu, Dechun Geng   +11 more
wiley   +1 more source