Results 261 to 270 of about 210,637 (357)

Differential roles of EA‐TRAPed cells in the anterior cingulate cortex across various intervention times in inflammatory pain

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The cumulative effect of EA analgesia is partially attributed to the activation of EA‐TRAPed cells in ACC. Multiple EA sessions and single EA sessions activated different neuronal populations in the ACC. The enhanced analgesic effect of multiple EA sessions may be attributed to an increase in the proportion of GABAergic neurons within the ACC. Abstract
Zi Guo   +8 more
wiley   +1 more source

Development of an in situ small intestinal injection technique for targeted macromolecule delivery and in vivo functional studies in mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study developed a minimally invasive, in situ small intestinal injection technique for mice, enabling targeted delivery of bioactive molecules while bypassing gastric degradation. Validation using functional assays and single‐cell RNA sequencing reveals high‐mobility group box 1–mediated epithelial responses, offering a translational tool for gut ...
Yawen Lai   +7 more
wiley   +1 more source

Thin is required for cell death in the Drosophila abdominal muscles by targeting DIAP1. [PDF]

open access: yesCell Death Dis, 2018
Vishal K   +4 more
europepmc   +1 more source

Establishment of a mouse model of TMAO‐induced cardiac injury and application of MICT intervention

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study aims to explore the establishment of an animal model of cardiac injury induced by trimethylamine‐N‐oxide (TMAO), a metabolite secreted by gut microorganisms, and to investigate its application in moderate‐intensity continuous training (MICT) intervention.
Zhongping Xie   +4 more
wiley   +1 more source

Building a humane scientific future: Second Asia Laboratory Animal Day

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Frontiers in Laboratory Animal Handling and Experimental Design: Bridging Ethics and Excellence Theme: Good Science with Good Care Ethical Framework: CCSEA & IAEC oversight | 3Rs (Replacement, Reduction, Refinement) | Transparent documentation Animal Handling & Anatomy: Mice • Rats • Rabbits • Guinea pigs Gentle restraint • Anatomical landmarks ...
Vijay Pal Singh   +3 more
wiley   +1 more source

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