Results 261 to 270 of about 205,580 (358)

Research advancements and evaluation of multifactor‐induced murine models for gastric cancer

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang   +5 more
wiley   +1 more source

Overexpression of transforming growth factor β1 in smooth muscle cells of human abdominal aortic aneurysm

open access: bronze, 2003
Daisuke Fukui   +5 more
openalex   +1 more source

Development of an efficient mice model of cancer‐associated cardiac cachexia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong   +9 more
wiley   +1 more source

The Vietnamese swine as a translational model of invasive ductal carcinoma of the breast

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The flow diagram outlines the chemical induction of breast tumors through a single intraperitoneal dose of MNU. Tumor development was assessed using ultrasound and clinical examination. After 14 weeks, mammary tissue was collected and histologically analyzed to evaluate structural similarities between sows and humans, the carcinogenic potential of MNU,
Claudia Elizabeth Vera‐Tizatl   +6 more
wiley   +1 more source

Cuneiform Nucleus Stimulation Can Assist Gait Training to Promote Locomotor Recovery in Individuals With Incomplete Tetraplegia

open access: yesAnnals of Neurology, EarlyView.
Objective Impaired ability to induce stepping after incomplete spinal cord injury (SCI) can limit the efficacy of locomotor training, often leaving patients wheelchair‐bound. The cuneiform nucleus (CNF), a key mesencephalic locomotor control center, modulates the activity of spinal locomotor centers via the reticulospinal tract.
Anna‐Sophie Hofer   +21 more
wiley   +1 more source

Dual‐Action 3D Bioprinted Scaffolds with MXene Quantum Dots for Tumor Suppression and Breast Tissue Regeneration Postmastectomy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Four types of 3D hydrogel scaffolds—acellular, acellular with MXene quantum dots (MQDs), cellular, and cellular with MQDs—are developed for postmastectomy breast cancer therapy. Among them, the acellular MQD scaffold uniquely prevents tumor recurrence while promoting tissue regeneration, offering a dual‐function platform that may reduce reliance on ...
Damla Alkaya   +10 more
wiley   +1 more source

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