Results 41 to 50 of about 206,637 (260)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Measurement of abdominal muscle thickness using ultrasound: A reliability study on patients with chronic nonspecific low back pain [PDF]

open access: yes, 2015
Background and purpose: The purpose of this study was to assess the Within-day and Between-days reliability of abdominal muscles size measurement in patients with chronic non-specific low back pain (LBP) using ultrasound (US).
Abdollahi, I.   +5 more
core  

Muscle Spasticity and Its Interaction with Myofascial System of Children with Central Paresis [PDF]

open access: yes, 2019
Traditionally, the problem of muscle spasticity was considered by experts as a kind of local problem associated with the inhibition or traumatisation of the central motor neuron in a certain part of its path.
Moga, N. (Nikolay)
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Neuromuscular systems in the fifth instar larva of silkworm Bombyx mori (Lepidoptera: Bombycidae): II- Abdominal musculature and its innervation [PDF]

open access: yes, 2009
The gross organisation of abdominal musculature and its innervation by segmental ganglionic nerves were studied in the fifth instar larva of Bombyx mori. The musculature comprises dorsal, ventral and lateral groups of muscles, represented as external and
Muralimohan, P., Sivaprasad, S.
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Correlation between abdominal and scapular muscle strength in upper back pain patients with and without scapulocostal syndrome

open access: yesJournal of Associated Medical Sciences, 2016
Objectives: To determine the correlation between strength of abdominal and scapular muscles in upper back pain patients with and without scapulocostal syndrome (SCS).
Wanatchaporn Supasatean   +6 more
doaj  

Automatic electrical stimulation of abdominal wall muscles increases tidal volume and cough peak flow in tetraplegia [PDF]

open access: yes, 2008
<p>Paralysis of the respiratory muscles in people with tetraplegia affects their ability to breathe and contributes to respiratory complications.
Allan, D.B.   +4 more
core  

Noninvasive assessment of inspiratory muscle neuromechanical coupling during inspiratory threshold loading [PDF]

open access: yes, 2019
Diaphragm neuromechanical coupling (NMC), which reflects the efficiency of conversion of neural activation to transdiaphragmatic pressure (Pdi), is increasingly recognized to be a useful clinical index of diaphragm function and respiratory mechanics in ...
Estrada Petrocelli, Luis Carlos   +6 more
core   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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