Results 81 to 90 of about 321,775 (350)

Waist Circumference predicting Cardiovascular Disease in Korean Men and Women [PDF]

, 2010
Objective: Obesity and cardiovascular disease (CVD) are closely related and have become increasingly prevalent in Korea. Asians are more prone to obesity-related co-morbidities than Caucasians, even at lower body mass index (BMI) and/or smaller waist ...
Sat Byul Park, Sun Ha Jee
core   +1 more source

Coronary age, based on coronary calcium measurement, is increased in patients with morbid obesity [PDF]

, 2018
Purpose: Obesity is a well-known of risk factor for atherosclerosis. However, recently an "obesity paradox" has been discussed, which is considered as a protective effect of obesity on the development coronary artery disease (CAD).
Białecki, Marcin, Hawrył, Mateusz, Lemanowicz, Adam, Leszczyński, Waldemar   +3 more
core   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Seamlessly Overcoming Biological Barriers with a Small Photosensitizer to Treat Metastatic Tumors with Photodynamic Therapy

Angewandte Chemie, EarlyView.
LUZ 51 is a relatively small and amphiphilic photosensitizer that accumulates in poorly‐vascularized tumors, is rapidly internalized by cancer cells, does not elicit skin photosensitivity and triggers robust immunological responses that reduce spontaneous metastasis.
Mafalda Penetra, Bárbara Lima, João P. A. Campos, Sara M. A. Pinto, Fábio A. Schaberle, Mariette M. Pereira, Luis G. Arnaut, Lígia C. Gomes‐da‐Silva   +7 more
wiley   +2 more sources

An updated study protocol for a real-life digital 12-month weight management program, the Healthy Weight Coaching

Annals of Medicine
Obesity is an important health concern that poses many public health challenges. Evidence-based treatment modalities, capable of cost-effectively reaching large patient groups are needed.
Aila J. Ahola, Anu Joki, Laura U. Suojanen, Kirsi H. Pietiläinen   +3 more
doaj   +1 more source

Perivascular adipose tissue as a relevant fat depot for cardiovascular risk in obesity [PDF]

, 2018
Obesity is associated with increased risk of premature death, morbidity, and mortality from several cardiovascular diseases (CVDs), including stroke, coronary heart disease (CHD), myocardial infarction, and congestive heart failure.
Costa, Rafael M., Lobato, Núbia S., Neves, Karla B., Tostes, Rita C.   +3 more
core   +3 more sources

Hyposomatotropism Blunts Lipolysis in Abdominally Obese Women [PDF]

Journal of Clinical Endocrinology & Metabolism, 2002
Abdominal obesity is associated with reduced 24-h plasma GH concentrations. It is unclear whether hyposomatotropism in abdominally obese humans is compensated by up-regulation of GH receptor sensitivity or causes less biological effect in target tissues.
Buijs, Madelon M., Burggraaf, Jacobus, Langendonk, Janneke G., Schoemaker, Rik C., Frölich, Marijke, Arndt, Jan-Willem, Cohen, Adam F., Romijn, Johannes A., Ackermans, Mariette T., Sauerwein, Hans P., Meinders, A. Edo, Pijl, Hanno   +11 more
openaire   +3 more sources

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Tracking and risk of abdominal and general obesity in children between 4 and 9 years of age. The Longitudinal Childhood Obesity Study (ELOIN)

BMC Pediatrics, 2022
Background Studies have shown that overweight and obesity conditions tend to be stable from childhood and adolescence to adulthood. Unfortunately, little is known about the evolution of abdominal obesity during childhood.
Honorato Ortiz-Marrón, Maira Alejandra Ortiz-Pinto, Gloria Cabañas Pujadas, José Galo Martínez Mosquera, Marien Lorente Miñarro, Francisca Menchero Pinos, María Ordobás Gavín, Iñaki Galán   +7 more
doaj   +1 more source

Gender-Related Differences in the Prevalence of Cardiovascular Disease Risk Factors and their Correlates in Urban Tanzania. [PDF]

, 2009
\ud Urban areas in Africa suffer a serious problem with dual burden of infectious diseases and emerging chronic diseases such as cardiovascular diseases (CVD) and diabetes which pose a serious threat to population health and health care resources ...
AA Motala, AB Swai, AC Perry, Alfa Muhihi, AR Walker, D Filmer, D Hu, D Lasky, D Spiegelman, DL Christensen, Donna Spiegelman, E Ford, E Sobngwi, E Sobngwi, Ellen Hertzmark, Enju Liu, H Schroder, H Schultz, HH Vorster, J Chalmers, J Koerselman, Jacob Mtabaji, JP Despres, Julia L Finkelstein, K Jagoe, K Tibazarwa, KG Alberti, KY Liang, M Njelekela, M Siervo, MA Van der Sande, Marina A Njelekela, ME Mendelsohn, MR Akpa, NCEP, Nuru L Mligiliche, P Bovet, P Pasquet, R Fuentes, Rose Mpembeni, S Mendis, SM Smith, TJ Aspray, W Willet, Wafaie W Fawzi, Walter C Willett, WC Chumlea, WHO, WT Friedewald   +48 more
core   +4 more sources