Results 101 to 110 of about 2,946,246 (355)

Hepatitis E Virus ORF1 Polyprotein Harbors a Pocket‐Like Cavity That Is Vital for Virus Replication and Represents a Novel Antiviral Target

Advanced Science, EarlyView.
Within the hepatitis E virus (HEV) ORF1 polyprotein, the X domain interacts with viral RNA‐dependent RNA polymerase (RdRp), forming a functional “pocket‐like” cavity (PC) that is crucial for viral replication. Structure‐based screening, surface plasmon resonance (SPR) assays, and HEV model validation collectively identify saikosaponin D and ...
Xiaohui Ding, Dou Zeng, Dan Liu, Yingying Bian, Bin Li, Zheng Li, Qiudi Li, Shiquan Liang, Yunlong Si, Qili Yao, Yibo Ding, Jiahui Zhu, Xiangyang Li, Kuiyang Zheng, Hongbo Guo, Wenshi Wang   +15 more
wiley   +1 more source

Incidence of abdominal pain due to the anterior cutaneous nerve entrapment syndrome in an emergency department

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2015
BackgroundPatients with chronic abdominal pain occasionally suffer from the anterior cutaneous nerve entrapment syndrome (ACNES). A substantial number of patients report previous visits to an emergency department (ED) with acute pain.
T. van Assen, J. Brouns, M. Scheltinga, R. Roumen   +3 more
semanticscholar   +1 more source

Inhibiting Liver‐Derived C3 Protein Rescues Anesthesia/Surgery‐Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis

Advanced Science, EarlyView.
This study provides evidence that anesthesia/surgery can induce the BBB breakdown and promote the release of hepatogenous C3 protein into the blood. This surgical dual factors ultimately drove C3 to cross the damaged BBB and selectively colocalize with C3aR in the hippocampus, which results in structural and functional injury of synapse, C3aR‐mediated ...
Qianqian Wu, Peilin Cong, Zhouxiang Li, Yuxin Zhang, Huanghui Wu, Qian Zhang, Yawei Li, Li Tian, Qingyuan Miao, Yinggang Zheng, Hui Zhang, Qian Chen, Enduo Feng, Xinyang Li, Zheping Chen, Dong‐Xin Wang, Xinwei Huang, Lize Xiong   +17 more
wiley   +1 more source

Outcome of nonspecific abdominal pain in the discharged patients from the emergency department

مجله دانشگاه علوم پزشکی گرگان, 2014
Background and Objective: The causes of non traumatic abdominal pain are varied from mild to severe onset. This study was carried out to assess the outcome of the patients with non-specific abdominal pain discharged from the emergency department. Methods:
Forouzanfar MM, Hatamabadi HR, Hashemi B, Majidi A, Baratloo A, Shahrami A, Bardeh M   +6 more
doaj  

The Effectiveness of Cognitive-Behavioral Play Therapy (CBT) and Resiliency Based Play Therapy on Sleep Disorder in Children with Functional Abdominal Pain [PDF]

, 2020
Shekoufeh Nikneshan, Mohsen Golparvar, Ahmad Abedi, Peiman Nasri, Fatemeh Famouri   +4 more
openalex   +1 more source

Comparison of the Effects of pH-Dependent Peppermint Oil and Synbiotic Lactol (Bacillus coagulans + Fructooligosaccharides) on Childhood Functional Abdominal Pain: A Randomized Placebo-Controlled Study

Iranian Red Crescent Medical Journal, 2015
Background: Still there is no consensus on the best treatment for abdominal pain-related functional Gastrointestinal Disorders (FGIDs). Objectives: The purpose of this study was to compare the effects of a synbiotic Lactol (Bacillus coagulans ...
M. Asgarshirazi, M. Shariat, Hosein Dalili   +2 more
semanticscholar   +1 more source

Realgar‐Induced CNS Toxicity: Exploring OTC‐Mediated Ornithine Regulation of ZBTB7A Inhibits Astrocyte Glycolysis Based on the Liver–Brain Axis

Advanced Science, EarlyView.
Arsenic in realgar induces CNS toxicity through direct and indirect effects: it activates ZBTB7A in astrocytes, which in turn inhibits glycolysis and impairs mice's learning, memory, and exploration; it also suppresses OTC in the liver to block the ornithine cycle, leading to blood ornithine accumulation that crosses into the frontal lobe and further ...
Ping Ye, Zhen Li, Huanyong Fu, Shuai Wang, Xingang Cui, Chengbo Song, Chao Ma, Hong Jiang   +7 more
wiley   +1 more source

A Novel One-Stop Multidisciplinary Clinic for Chronic Postoperative Inguinal Pain: Initial Experiences and Outcomes

Journal of Abdominal Wall Surgery
BackgroundChronic Postoperative Inguinal Pain (CPIP) affects 10%–20% of patients following inguinal hernia repair, persisting for over 3 months post-surgery.
Federica Cocciolo, Alice Birch, Maciej Pawlak, Lucy Miller, Alan Bennett, Matthew Lund, David Sanders, John M. Findlay, John M. Findlay, John M. Findlay   +9 more
doaj   +1 more source

Construction and validation of a questionnaire distinguishing a chronic abdominal wall pain syndrome from irritable bowel syndrome [PDF]

, 2012
Tijmen van Assen, Oliver B. Boelens, Jan T Kamphuis, Marc R. Scheltinga, Rudi M. H. Roumen   +4 more
openalex   +1 more source

Health Outcomes in US Children with Abdominal Pain at Major Emergency Departments Associated with Race and Socioeconomic Status

PLoS ONE, 2015
Objective Over 9.6 million ED visits occur annually for abdominal pain in the US, but little is known about the medical outcomes of these patients based on demographics.
Louise L Wang, C. Haberland, C. Thurm, J. Bhattacharya, K. Park   +4 more
semanticscholar   +1 more source