Results 121 to 130 of about 2,955,479 (401)

Paediatric functional abdominal pain disorders

open access: yesNature Reviews Disease Primers, 2020
N. Thapar   +10 more
semanticscholar   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

open access: yesAdvanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun   +23 more
wiley   +1 more source

A Novel One-Stop Multidisciplinary Clinic for Chronic Postoperative Inguinal Pain: Initial Experiences and Outcomes

open access: yesJournal of Abdominal Wall Surgery
BackgroundChronic Postoperative Inguinal Pain (CPIP) affects 10%–20% of patients following inguinal hernia repair, persisting for over 3 months post-surgery.
Federica Cocciolo   +9 more
doaj   +1 more source

Abdominal pain syndrome in children and adolescents: treatment options

open access: yesZdorovʹe Rebenka, 2018
Abdominal pain is a frequent cause for patients of different age groups to consult a doctor, and one of the most frequent complaints of children and their parents.
О.V. Shutova
doaj   +1 more source

Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins

open access: yesAdvanced Science, EarlyView.
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan   +14 more
wiley   +1 more source

Aloe‐Emodin Targeting FOXC2 Disrupts NETs Formation and EMT‐Driven Postoperative Peritoneal Adhesion Through TGF‐β1‐Smad2/3 Pathway

open access: yesAdvanced Science, EarlyView.
Forkhead box protein C2 (FOXC2) is highlighted as a pivotal effector in postoperative peritoneal adhesion (PPA) formation. Mechanically, FOXC2 mediates NETs‐induced EMT alterations through the TGF‐β1‐Smad2/3 pathway. Aloe‐emodin (AE) ameliorates FOXC2‐driven fibrosis by blocking NETs formation and EMT changes through this pathway.
Lili Yang   +10 more
wiley   +1 more source

Chronic Abdominal Discomfort Syndrome (CADS): A Narrative Review of Treatment Strategies

open access: yesJournal of Pain Research
Mayank Gupta,1,* Anand S Patil,2,* Peter Staats,3 Michael E Schatman,4 Hemant Kalia,5 Dawood Sayed,6 Amol Soin,7 Ganesan Baranidharan,8 Leonardo Kapural,9 Ahish Chitneni,10 Paul Verrills,11 Sudhir Diwan,12 Alaa A Abd-Elsayed,13 Timothy R ...
Gupta M   +13 more
doaj  

Two Cases of Primary Ectopic Ovarian Pregnancy [PDF]

open access: yes, 2011
Primary ovarian pregnancy is one of the rarest varieties of ectopic pregnancies. Patients frequently present with abdominal pain and menstrual irregularities. Intrauterine devices have evolved as probable risk factors.
Ghosal, T   +3 more
core   +1 more source

A woman with abdominal pain [PDF]

open access: yesJACEP Open, 2021
Yuan‐Jen Chen   +7 more
openaire   +3 more sources

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