Results 181 to 190 of about 2,789,686 (396)

Gut Microbiome Pilot Study of Patients With CHARGE Syndrome and Sibling Controls

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Difficulties with feeding and digestion are common in individuals with CHARGE syndrome. Animal models with CHD7 gene variants demonstrate abnormal gut innovation and dysmotility. Our pilot study evaluated whether individuals with CHARGE syndrome have differences in their gut microbiome compared to unaffected siblings.
Emily R. Chedrawe   +5 more
wiley   +1 more source

Hereditary angioedema: a rare cause of recurrent abdominal pain [PDF]

open access: green, 1969
Xi Chen   +4 more
openalex   +1 more source

Abdominal and testicular pain: An atypical presentation of COVID-19

open access: yesAmerican Journal of Emergency Medicine, 2020
Jesi Kim   +3 more
semanticscholar   +1 more source

In vivo toxic and lethal cardiorespiratory effects of a synthetic quaternary ammonium salt derivative of haloperidol in mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Hematoxylin–eosin (H&E) stains of the heart, liver, lung, and kidney show acute toxicity. Abstract Background To investigate the toxicity of N‐n‐butyl haloperidol iodide (F2), a quaternary ammonium salt derivative of haloperidol, in mice for potential therapeutic purposes. Methods The acute median lethal dose (LD50) of F2 was determined using the Bliss
Jilin Liao   +6 more
wiley   +1 more source

Pharmacokinetic analysis on compatibility of Atractylodes macrocephala and Paeoniae radix herb pair ameliorates functional constipation model rats using microdialysis with ultra‐performance liquid chromatography

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The active ingredient of the drug determines the effect of the drug, and the compatibility affects the content of the active ingredient of the drug, which in turn affects the exertion of the efficacy. This study partly clarifies the rationality and compatibility of AM‐PR in the treatment of FC.
Xiaoting Wang   +4 more
wiley   +1 more source

Chronic Abdominal Discomfort Syndrome (CADS): Defining and Discussing a Novel Diagnosis

open access: yesJournal of Pain Research
Mayank Gupta,1,* Anand S Patil,2,* Ahish Chitneni,3 Michael E Schatman,4 Hemant Kalia,5 Timothy R Deer,6 Dawood Sayed,7 Amol Soin,8 Ganesan Baranidharan,9 Peter Staats,10 Leonardo Kapural,11 Phani Ashok Attaluri,12 Paul Verrills,13 Sudhir Diwan ...
Gupta M   +16 more
doaj  

Comprehensive Analysis of Bioactive Peptides from Cuminum cyminum L. Seeds: Sequence Identification and Pharmacological Evaluation [PDF]

open access: yesarXiv
Cuminum cyminum L. (cumin) is a medicinal and edible plant widely used in traditional Chinese medicine (TCM) for treating various ailments, including diarrhea, abdominal pain, inflammation, asthma, and diabetes. While previous research has primarily focused on its essential oils, studies on its protein-derived bioactive peptides remain limited. In this
arxiv  

Yunweiling alleviates functional constipation: integrating network pharmacology and experimental study

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang   +6 more
wiley   +1 more source

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