Results 211 to 220 of about 807,581 (353)

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

Recurrent pediatric abdominal pain

Journal of the American College of Emergency Physicians Open, 2021
Joseph Romero, Grant S. Lipman
doaj   +1 more source

A Patient with an Unusual Cause of Acute Left Flank and Lower Abdominal Pain. [PDF]

Kidney360
Husain-Syed F, Harth S.
europepmc   +1 more source

Early Indicators Of ‘Critical’ Outcomes In Horses Presenting With Abdominal Pain (Colic): Retrospective Study Of ‘Out Of Hours’ First Opinion Emergency Cases From Two Practices Over A Three Year Period (2011–2013) [PDF]

, 2017

openalex   +1 more source

The persistence of chronic opioid use in patients with inflammatory bowel disease—A nationwide cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aims Pain is common in patients with Crohn's disease (CD) and ulcerative colitis (UC), and a substantial proportion develop chronic opioid use (COU). We examined the persistence of COU over time and identified factors predicting persistent use. Methods This nationwide Danish cohort study included patients with an initial period of COU (definition: ≥3 ...
Bente Mertz Nørgård, Caroline Theilgaard Thorarinsson, Jan Nielsen, Mette Louise Andersen, Jens Kjeldsen, Torben Knudsen, Rahul S. Dalal   +6 more
wiley   +1 more source

Severe Abdominal Pain Mimicking Appendicitis Caused by Imperforate Hymen: Case Report and Narrative Review. [PDF]

Pediatr Rep
Kleina J, Wieczorek M, Markowska K, Nierzwicka K, Leszkowicz J, Szlagatys-Sidorkiewicz A.   +5 more
europepmc   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Median arcuate ligament syndrome: a rare cause of postprandial abdominal pain - a case report with review of literature. [PDF]

J Surg Case Rep
Farooqui A, Ahmad M, Sadiq A, Ali WM, Alam S.   +4 more
europepmc   +1 more source

Measuring irritable bowel syndrome patient‐reported outcomes with an abdominal pain numeric rating scale [PDF]

, 2009
Brennan Spiegel, Roger Bolus, Lucinda A. Harris, Susan Lucak, Bruce D. Naliboff, Eric Esrailian, William D. Chey, Anthony Lembo, Hetal A. Karsan, Kirsten Tillisch, Jennifer Talley, Emeran A. Mayer, Lin Chang   +12 more
openalex   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source