Results 241 to 250 of about 807,581 (353)

Self‐Management Interventions in Young Adults (18–30 Years) With Type 1 Diabetes, Sickle Cell Disease, and Inflammatory Bowel Disease: A Scoping Review

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Fluctuating chronic conditions (FCC) in young adults aged 18–30 years, such as type 1 diabetes (T1D), sickle cell disease (SCD), and inflammatory bowel disease (IBD), present unique self‐management challenges due to unpredictable symptom patterns that disrupt daily life.
Reham Almabadi   +3 more
wiley   +1 more source

Man with abdominal pain

open access: yesJournal of the American College of Emergency Physicians Open, 2020
Sophie Leflot   +3 more
doaj   +1 more source

Emerging therapeutic approaches for treating abdominal pain. [PDF]

open access: yesJ Can Assoc Gastroenterol
Jimenez-Vargas NN   +6 more
europepmc   +1 more source

A multipart phase 1 study of the safety, pharmacodynamics and pharmacokinetics of ALG‐055009, a novel thyroid hormone receptor beta (THR‐β) agonist for metabolic dysfunction‐associated steatohepatitis (MASH), in healthy participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract ALG–055009 is an oral thyroid hormone receptor beta (THR‐β) agonist being evaluated for treating metabolic dysfunction–associated steatohepatitis (MASH). This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALG‐055009 and bioavailability/food effect.
Hakim Charfi   +11 more
wiley   +1 more source

Pheochromocytoma: A rare cause of abdominal pain identified in a family medicine outpatient department setting. [PDF]

open access: yesJ Family Med Prim Care
Teja S   +5 more
europepmc   +1 more source

A Phase 1, Randomized, Open‐Label, Parallel Group Study to Evaluate the Relative Bioavailability and Safety of Subcutaneous Bepirovirsen when Delivered from a Vial or Prefilled Syringe Fitted with a Safety Syringe Device in Healthy Adult Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Bepirovirsen, an antisense oligonucleotide in development for the treatment of chronic hepatitis B virus (HBV) infection, is administered from glass vials as a subcutaneous (SC) injection by healthcare professionals (HCPs). A ready‐to‐use prefilled syringe (PFS) assembled with a safety syringe device (SSD) has been developed to make ...
Amir S. Youssef   +15 more
wiley   +1 more source

954 Carbohydrate Digestion in Congenital Sucrase Isomaltase Deficient and Recurrent Abdominal Pain Children Assesed by 13C- Starch Breath Test

open access: bronze, 2010
Claudia C. Robayo‐Torres   +5 more
openalex   +1 more source

Quantitative Systems Toxicology Modeling with DILIsym to Support Phase 3 Dose Selection for Fezolinetant

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Fezolinetant is a first‐in‐class, selective, non‐hormonal, neurokinin 3 receptor antagonist that is approved for the treatment of moderate to severe vasomotor symptoms due to menopause. In a phase 2b clinical study (n = 352), nine study participants experienced elevations in serum transaminases exceeding three times the upper limit of normal.
Jace C. Nielsen   +11 more
wiley   +1 more source

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