Results 151 to 160 of about 784,791 (313)

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

open access: yesAdvanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao   +9 more
wiley   +1 more source

Outcome on Surgical Site Infections for the Closure of Abdominal Incisions in General Surgery

open access: gold, 2022
Shiraz Shaikh   +5 more
openalex   +2 more sources

Implementation interventions in preventing surgical site infections in abdominal surgery: a systematic review [PDF]

open access: gold, 2020
Ivonne Tomsic   +5 more
openalex   +1 more source

AI‐Assisted Detection of Early Gastric Cancer via Visualization of Mucosal Acidity Compromise During Endoscopy

open access: yesAdvanced Science, EarlyView.
An AI‐assisted SERS system is developed to rapidly and reliably detect early gastric cancer by visualizing gastric mucosal acidity, enhancing endoscopic differentiation, improving guidance for submucosal dissection, and reducing false‐positive diagnoses.
Huihui Yan   +18 more
wiley   +1 more source

Genipin-crosslinked gelatin microspheres as a strategy to prevent postsurgical peritoneal adhesions : in vitro and in vivo characterization [PDF]

open access: yes, 2016
Bracke, Marc   +7 more
core   +1 more source

A Hypoxia‐Responsive Single‐Atom Sonozyme for Targeted Sonocatalytic Therapy in Alleviating Atherosclerotic Plaque

open access: yesAdvanced Science, EarlyView.
A tetranitrogen‐coordinated single‐atom manganese catalyst (SMC) is fabricated with outstanding sonosensitization efficiency and multi‐enzyme‐like catalytic properties. To enable better targeting of M1 macrophages, hyaluronic acid (HA) is applied to modify the surface of SMC, yielding SMC‐HA nanozymes.
Qiaofei Chen   +14 more
wiley   +1 more source

ZFPL1 Promotes Colorectal Cancer Progression by Stabilizing ASS1 to Drive the Urea Cycle and M2 Macrophage‐Mediated Metastatic Colonization

open access: yesAdvanced Science, EarlyView.
ScRNA‐seq reveals ZFPL1‐specific enrichment in malignant CRC cells. Mechanistically, ZFPL1 stabilizes ASS1 by blocking K57 ubiquitination, activating urea cycle metabolism to drive progression. ZFPL1 inhibition reprograms the TME by suppressing M2 macrophages polarization and promotion M1 macrophages, thereby inhibiting CRC liver metastasis ...
Xiangjun Qian   +14 more
wiley   +1 more source

Engineered Substrate‐Free Small Molecules for Enhanced Raman Scattering and Photothermal Conversion Efficiency

open access: yesAdvanced Science, EarlyView.
A molecular engineering strategy is developed to increase the stacking‐induced intermolecular charge transfer‐enhanced Raman scattering (SICTERS) intensity and photothermal conversion efficiency of electron donor‐acceptor‐donor (D–A–D) molecules. This approach enables to design SICTERS‐mediated photo‐theranostic agents for substrate‐free Raman image ...
Sheng Yu   +9 more
wiley   +1 more source

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

open access: yesAdvanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu   +13 more
wiley   +1 more source

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