Prone positioning in acute respiratory distress syndrome after abdominal surgery [PDF]
, 2015 Stéphane Gaudry +8 more
openalex +1 more source
Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities
Advanced Science, EarlyView.This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao +21 more
wiley +1 more source
Immediate breast reconstruction with a ‘modified fleur-de-lis’ abdominal-free flap in a patient with previous abdominal surgery [PDF]
, 2018 Manuel Robustillo +5 more
openalex +1 more source
Advanced Science, EarlyView.This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng +7 more
wiley +1 more source
TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy
Advanced Science, EarlyView.We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng +9 more
wiley +1 more source
MODERN INNOVATIVE TECHNOLOGIES IN ABDOMINAL SURGERY
, 2017 С. І. Саволюк +2 more
openalex +2 more sources
Response to: Modified Rockwood frailty index is predictive of adverse outcomes in elderly populations undergoing major abdominal surgery: is it a practical tool though? [PDF]
, 2021 Jorge Humberto Rodríguez-Quintero +3 more
openalex +1 more source
Magnetically‐Induced Suppression of Oxidative Stress Prevents Venous Thrombosis
Advanced Science, EarlyView.Venous thromboembolism (VTE) remains a leading cause of cardiovascular mortality. This study demonstrates that static magnetic fields (SMF) offer a novel non‐pharmacological intervention against VTE by mitigating endothelial oxidative stress. Mechanistically, SMF elevates intracellular Ca2+, boosts ATP production, and suppresses NOX4‐mediated ROS ...
Nana Zhang +12 more
wiley +1 more source
More Restrictive Rectal Dose-volume Constraints Should be Applied to 3D-CRT Prostate Cancer Patients Who Underwent Previous Abdominal Surgery [PDF]
, 2009 T. Rancati +8 more
openalex +1 more source