Results 211 to 220 of about 2,214,716 (303)

LAPTM5 Downregulation‐Driven VAMP8 Phosphorylation Impairs Autophagosome‐Lysosome Fusion and Aggravates Septic Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
LAPTM5 functions as a critical molecular scaffold bridging PGAM5 and VAMP to facilitate PGAM5‐mediated dephosphorylation of VAMP8. This cascade promotes autophagosome‐lysosome fusion, restores impaired autophagic flux, and clears damaged mitochondria, thereby mitigating cellular oxidative stress and systemic inflammation.
Lang Jiang   +12 more
wiley   +1 more source

Prognosis of thyroid function after hemithyroidectomy

open access: yesOpen Medicine, 2011
Beiša V.   +5 more
doaj   +1 more source

NCOA4 Accelerates Abdominal Aortic Aneurysm Formation by Regulating Macrophage Activation and Ferroptosis via STAT1–CH25H Axis

open access: yesAdvanced Science, EarlyView.
Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu   +9 more
wiley   +1 more source

One‐Year Healthcare Utilization and Costs After Emergency Department Encounters for Uncomplicated Appendicitis: A Statewide Observational Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Objective Non‐operative management with antibiotics has emerged as an alternative to appendectomy for uncomplicated appendicitis. This study compared one‐year healthcare costs and utilization outcomes after operative versus non‐operative management of uncomplicated appendicitis using statewide administrative data.
Andrew C. Meltzer   +5 more
wiley   +1 more source

Patterns of patient worry following major emergency abdominal surgery: a 180-day follow-up study. [PDF]

open access: yesEur J Trauma Emerg Surg
Parner MK   +4 more
europepmc   +1 more source

Artificial Intelligence–Based Surgical Phase Analysis Enables Objective Assessment of Surgeon Skill in Robotic Distal Gastrectomy: A Multicenter Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Artificial intelligence (AI)–based surgical video analysis can automate time‐consuming manual assessments and enable objective characterization of surgical workflows. We aimed to construct a large, multicenter, fully annotated dataset of robotic distal gastrectomy (RDG) videos and evaluate the feasibility and performance of an AI model for
Masaru Komatsu   +8 more
wiley   +1 more source

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