Results 201 to 210 of about 121,365 (288)

A Randomized Phase 1 Study Evaluating Pharmacokinetics, Safety, and Tolerability of a High‐Concentration, Long‐Acting Cabotegravir Formulation in Adults Without HIV

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Long‐acting (LA) cabotegravir 200‐mg/mL (CAB200) injections are approved for HIV‐1 prevention and as a complete LA HIV‐1 treatment regimen with rilpivirine. A high‐concentration suspension formulation, cabotegravir 400 mg/mL (CAB400‐D), was developed to enable less frequent dosing and self‐administration. This phase 1, double‐blind, randomized
Kelong Han   +16 more
wiley   +1 more source

Common hepatic bile duct partial transection: a rare consequence of blunt abdominal trauma. A case report and brief narrative review. [PDF]

open access: yesJ Surg Case Rep
Abdelgawad M   +8 more
europepmc   +1 more source

First‐in‐Human Phase 1 Study to Evaluate the Clinical Pharmacology Properties of RBN‐3143, a Novel Inhibitor of Mono‐Adenosine Diphosphate Ribosyltransferase‐PARP14

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract RBN‐3143 is an inhibitor of PARP14 in development for inflammatory diseases. Multiple assessments were conducted to evaluate the clinical pharmacology properties of RBN‐3134. A randomized, double‐blind, placebo‐controlled study assigned healthy volunteers (HVs) to single ascending doses (SADs) (25‐1000 mg) or multiple ascending doses (MADs ...
Thomas M. Polasek   +9 more
wiley   +1 more source

Self‐Disgust, Body‐Related Attentional Bias and Body Dissatisfaction: A Virtual Reality and Eye‐Tracking Exploration

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study examines the relationships between self‐disgust, body dissatisfaction (BD), and attentional biases (AB) toward weight‐related body areas, exploring whether self‐disgust predicts attentional avoidance and moderates the relationship between BD and AB.
Mariarca Ascione   +6 more
wiley   +1 more source

Ruptured Parasitic Dermoid Cyst in Blunt Abdominal Trauma. [PDF]

open access: yesEast Afr Health Res J
Nuwass EQ   +4 more
europepmc   +1 more source

Stomach Transection due to Blunt Abdominal Trauma: A Case Report

open access: hybrid, 2003
Toshiyuki Nakamura   +5 more
openalex   +2 more sources

Think highly of immunoglobulin G4‐related chronic rhinosinusitis as a clinical entity in immunoglobulin G4‐related disease

open access: yesEye &ENT Research, EarlyView.
Abstract IgG4‐related chronic rhinosinusitis (IgG4‐related CRS) is gaining recognition among various specialized physicians. As a systemic disease involving multiple organs, IgG4‐related CRS is still not widely recognized as an independent clinical entity. Given the complexity of diagnosing autoimmune‐related multisystem diseases, early recognition and
Lianqi Wan   +3 more
wiley   +1 more source

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