Results 271 to 280 of about 1,557,968 (377)

SOX6 enhances vascular smooth muscle cell phenotypic switching and elevates blood pressure by activating autophagy

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Sox6 expression is elevated in hypertensive conditions and promotes vascular smooth muscle cell phenotypic switching through autophagy activation. Using gain‐ and loss‐of‐function approaches both in vitro and in vivo, we demonstrate that Sox6 regulates blood pressure and vascular remodeling, highlighting its potential as a novel therapeutic target for ...
Qianhui Ling   +7 more
wiley   +1 more source

Achieving scalable expansion of therapeutic porcine hepatocytes in vivo through serial transplantation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This represents the first serial hepatocyte transplantation pig model designed to investigate the massive hepatocyte proliferation in vivo. Leveraging this novel model, we achieved serial hepatocyte transplantation and regeneration in a porcine model, where the transplanted hepatocytes effectively repopulated the livers of two‐generation model pigs in ...
Zhiqiang Han   +10 more
wiley   +1 more source

Predictive factors of mortality in patients with abdominal trauma. [PDF]

open access: yesUlus Travma Acil Cerrahi Derg
Turan ÖF   +6 more
europepmc   +1 more source

Development of an efficient mice model of cancer‐associated cardiac cachexia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong   +9 more
wiley   +1 more source

Two Cases of Blunt Abdominal Trauma with CT Findings Mimicking those of Intraperitoneal Free Air: A Pitfall of High-Performance CT

open access: bronze, 2003
Yoshihiro Moriwaki   +6 more
openalex   +2 more sources

Research progress on traditional Chinese medicine animal models of post‐stroke depression and pathological insights

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Post‐stroke depression (PSD) animal model of traditional Chinese medicine (TCM) combined with disease and syndrome often uses western medicine surgery (including: middle cerebral artery embolization to construct cerebral ischemia, or brain injection of collagenase to construct cerebral hemorrhage) combined with other methods (including: isolation ...
Jielin Wang   +4 more
wiley   +1 more source

Addressing abdominal trauma from conflict and warfare in under-resourced regions: A critical narrative review. [PDF]

open access: yesHealth Sci Rep
Awuah WA   +12 more
europepmc   +1 more source

Towards Polymer Composite‐Based Transient Electronic Systems

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biodegradable electronic systems are gaining attention for implantable biomedical applications, targeting disease treatment and lifespan extension. This review covers advances in biocompatible, biodegradable polymer composites using synthetic and natural polymers with conductive, semiconductive, and insulating fillers.
Gwan‐Jin Ko   +5 more
wiley   +1 more source

Stomach Transection due to Blunt Abdominal Trauma: A Case Report

open access: hybrid, 2003
Toshiyuki Nakamura   +5 more
openalex   +2 more sources

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