Results 81 to 90 of about 37,904 (291)

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

Animal Models and Experimental Medicine, EarlyView.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

A Clinical study on Hollow Viscus Injuries in Abdominal Trauma [PDF]

, 2019
INTRODUCTION: Abdominal injuries are the third most common injuries caused by trauma which includes both blunt and penetrating injuries affecting solid or hollow visceral organs or vascular structures with various modes of presentations ranging from ...
Amritha, Subramonian
core  

Canine brachycephalic obstructive airway syndrome as a model for studying the effects of obstructive sleep apnea during pregnancy

Animal Models and Experimental Medicine, EarlyView.
We observed a negative effect of brachycephalic obstructive airway syndrome (BOAS) in a staggered manner based on the severity of the condition on respiratory and cardiac patterns, glycemia, acid–base balance, fetal growth, and uterine artery hemodynamics, thus requiring adaptations within the fetal–placental unit. Severely affected bitches had uterine
Roberto Rodrigues da Rosa Filho, Thayná Pantoja Gardés, Maíra Morales Brito, Leticia Lima de Almeida, Camila Infantosi Vannucchi   +4 more
wiley   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

Traumatic avulsion of kidney and spleen into the chest through a ruptured diaphragm in a young worker: a case report

Journal of Medical Case Reports, 2007
Introduction Rupture of the diaphragm is almost always due to major trauma. Diaphragmatic injuries are rare (5–7%), usually secondary to blunt, or more rarely to penetrating, thoracic or abdominal trauma.
Stamatiou Konstantinos, Ilias Georgios, Chlopsios Christos, Karanasiou Vasilissa, Kavouras Nikolaos, Lebrun Fred, Heretis John, Sofras Frank   +7 more
doaj   +1 more source

Celiac dissection after blunt abdominal trauma complicated by acute hepatic failure: Case report and review of literature

, 2007
Injuries of the abdominal visceral vessels are uncommon but devastating entities resulting in extremely high rates of mortality. The most common cause of abdominal vascular injuries is penetrating trauma, accounting for 90% to 95% of these injuries.
Muetzel (Rauch), Elisabeth, Chlodwig Kirchhoff, Kanz, Karl-Georg, Kirchhoff, Chlodwig, Stegmaier, Julia, Bernhard Heindl, Michael Krotz, Krotz, Michael, Julia Stegmaier, Karl-Georg Kanz, Elisabeth Muetzel (Rauch), Heindl, Bernhard, Wolf Mutschler, Mutschler, Wolf   +13 more
core   +1 more source

From classroom to clinic: Evaluating the educational utility of two Thiel embalming methods

Anatomical Sciences Education, EarlyView.
Abstract Over three decades since its introduction, the Thiel embalming method remains a widely used and praised technique in anatomical education and clinical training. This study compared for the first time the Thiel original protocol (TO) and a Modified version (TM) across user groups—undergraduate medical students, student demonstrators in anatomy,
Veronica Antipova, Martin Siwetz, Simone Manhal, Niels Hammer   +3 more
wiley   +1 more source

The current management of penetrating cardiac trauma

, 2012
Includes bibliographical references.The vast majority of patients with penetrating cardiac injuries do not reach the hospital alive as the pre-hospital mortality rate for these injuries is in the region of 86%.
Nicol, Andrew John
core  

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

Endovascular stent grafting for superior mesenteric vein erosion in necrotizing pancreatitis: A lifesaving intervention in a rare complication

Radiology Case Reports
Vascular complications, though rare, significantly increase the morbidity and mortality associated with necrotizing pancreatitis (NP). While arterial pseudoaneurysms are well-documented, major venous injuries, particularly superior mesenteric vein (SMV ...
Sophia Humphrey, BS, Elias El-Haddad, MD, Manasa Veluvolu, MD, Zachary Warriner, MD, Andrew Bernard, MD, Driss Raissi, MD   +5 more
doaj   +1 more source