Results 71 to 80 of about 462,560 (364)

A Novel 3D High‐Throughput Phenotypic Drug Screening Pipeline to Identify Drugs with Repurposing Potential for the Treatment of Ovarian Cancer

Advanced Healthcare Materials, EarlyView.
Ovarian cancer's high recurrence and therapy resistance demand new strategies. A high‐throughput drug screening pipeline using 3D spheroids, which showed poor concordance with 2D models, identified rapamycin as a promising candidate. In combination with cisplatin, rapamycin demonstrated significant in vitro and in vivo efficacy, highlighting the ...
Nazanin Karimnia, Amy L. Wilson, Brittany R. Doran, Jennie Do, Amelia Matthews, Gwo Y. Ho, Magdalena Plebanski, Thomas W. Jobling, Andrew N. Stephens, Maree Bilandzic   +9 more
wiley   +1 more source

Transabdominal preperitoneal versus hybrid procedures for treating irreducible inguinal hernias: A retrospective controlled study

Asian Journal of Surgery, 2023
Background: Inguinal hernia is a common condition; however, irreducible inguinal hernias are rare. In this retrospective study, two laparoscopic procedures for irreducible inguinal hernia were compared.
Hongming Zhang, Zhen Cao, Jinxin Cao, Jie Chen, Yuchen Liu, Minggang Wang   +5 more
doaj  

Adipose-Derived Stem Cells Based on Electrospun Biomimetic Scaffold Mediated Endothelial Differentiation Facilitating Regeneration and Repair of Abdominal Wall Defects via HIF-1α/VEGF Pathway

Frontiers in Bioengineering and Biotechnology, 2021
Application of synthetic or biological meshes is the main therapy for the repair and reconstruction of abdominal wall defects, a common disease in surgery.
Wenpei Dong, Zhicheng Song, Suihong Liu, Ping Yu, Zhipeng Shen, Jianjun Yang, Dongchao Yang, Qinxi Hu, Haiguang Zhang, Yan Gu   +9 more
doaj   +1 more source

Simulation of bifurcated stent grafts to treat abdominal aortic aneurysms (AAA) [PDF]

, 2016
In this paper a method is introduced, to visualize bifurcated stent grafts in CT-Data. The aim is to improve therapy planning for minimal invasive treatment of abdominal aortic aneurysms (AAA). Due to precise measurement of the abdominal aortic aneurysm and exact simulation of the bifurcated stent graft, physicians are supported in choosing a suitable ...
arxiv   +1 more source

Bioprinting Perfusable and Vascularized Skeletal Muscle Flaps for the Treatment of Volumetric Muscle Loss

Advanced Healthcare Materials, EarlyView.
Volumetric muscle loss (VML) due to trauma or surgery, often leads to physical impairments. Traditional treatments rely on autologous flaps, limited by muscle availability often leading to donor site morbidity. This study presents multimodal bioprinting as an innovative approach for fabricating vascularized muscle flaps with 3D‐printed macrovessels ...
Eliana O. Fischer, Anna Tsukerman, Majd Machour, Margarita Shuhmaher, Asaf Silverstein, Maya Yaakov, Orit Bar‐Am, Lior Debbi, Shulamit Levenberg   +8 more
wiley   +1 more source

C6orf15 promotes liver metastasis via WNT/β-catenin signalling in colorectal cancer

Cancer Cell International
Background Colon cancer ranks third among global tumours and second in cancer-related mortality, prompting an urgent need to explore new therapeutic targets.
Jiankang Yu, Jian Sun, Jingtong Tang, Jiayu Xu, Guanru Qian, Jianping Zhou   +5 more
doaj   +1 more source

Laparoscopic umbilical hernia repair in the presence of extensive paraumbilical collateral veins: A case report [PDF]

, 2011
A patient with an umbilical hernia presenting with collateral veins in the abdominal wall and umbilicus is a case that every hernia surgeon has to deal with occasionally.
Eker, H.H. (Hasan), Goede, B. (Barry) de, Kazemier, G. (Geert), Klitsie, P.J. (Pieter), Lange, J.F. (Johan), Lases, S.S. (Seilenna), Peeters, M.P.F.V., Pierik, E.G.J.M. (Robert)   +7 more
core   +2 more sources

Kinematics of Abdominal Aortic Aneurysms [PDF]

Journal of Biomechanics, 179, 112484 (2025)
A search in Scopus within "Article title, Abstract, Keywords" unveils 2,444 documents focused on the biomechanics of Abdominal Aortic Aneurysm (AAA), mostly on AAA wall stress. Only 24 documents investigated AAA kinematics, an important topic that could potentially offer significant insights into the biomechanics of AAA.
arxiv   +1 more source

Numerical investigation of abdominal aortic aneurysm hemodynamics using the reduced unified continuum formulation for vascular fluid-structure interaction [PDF]

arXiv, 2022
We recently demonstrated the reduction of the unified continuum and variational multiscale formulation to a computationally efficient fluid-structure interaction (FSI) formulation via three sound modeling assumptions pertaining to the vascular wall.
arxiv  

A Dual‐Layer Hydrogel Barrier Integrating Bio‐Adhesive and Anti‐Adhesive Properties Prevents Postoperative Abdominal Adhesions

Advanced Healthcare Materials, EarlyView.
A new dual‐layer hydrogel barrier for preventing postoperative abdominal adhesions is developed. The inner layer, consisting of polyethyleneimine (PEI) and thioctic acid (TA), enhanced adhesion to moist tissues. The outer layer combines zwitterionic, thermoresponsive hyaluronic acid with anti‐inflammatory epigallocatechin gallate (EGCG) and forms a ...
Mena Asha Krishnan, Olawale A. Alimi, Mitchell Kuss, Tiffany N Razabdouski, Erika A Eksioglu, Bin Duan, Bo Liu   +6 more
wiley   +1 more source