Results 261 to 270 of about 79,600 (334)
Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
The Space Within: How Architected Voids Promote Tissue Formation
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou +3 more
wiley +1 more source
ABSTRACT Heterozygous pathogenic variants in TBX3 cause Ulnar‐Mammary syndrome (UMS). The phenotype is classically characterized by upper limb defects, apocrine/mammary gland hypoplasia, hypogonadism, and various midline defects. However, the clinical spectrum is highly variable, and some individuals may present with a mild or atypical presentation ...
Ziv Halperin, Karin Weiss
wiley +1 more source
Blunt trauma-induced abdominal wall hernia with small bowel incarceration: case report and review of the literature. [PDF]
Ben Ismail I +5 more
europepmc +1 more source
Implantable Drug Delivery Systems for Skeletal Muscles and Eyes
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov +8 more
wiley +1 more source
Revisiting Spigelian hernia with emphasis on diagnostic challenges and outcomes of open mesh repair: a case report of two patients. [PDF]
Ogut E, Yildirim FB, Memis O.
europepmc +1 more source
ABSTRACT Background Congenital anomalies (CAs) are a major cause of childhood mortality and disability in low‐ and middle‐income countries. Our study explored caregiver experiences of infants with major CAs in Kenya and co‐developed interventions using human‐centered design (HCD).
Audrey Chepkemoi +17 more
wiley +1 more source
Severe Supravalvular Aortic Stenosis Treated With Double Patch Aortoplasty: A Case Report
ABSTRACT Severe supravalvular aortic stenosis in a young patient is a rare but critical condition requiring timely diagnosis and intervention. We report a 15‐year‐old girl presenting with exertional dyspnea, chest pain, and palpitations. Echocardiography and multidetector computed tomography (MDCT) confirmed severe supravalvular aortic stenosis ...
Birat Kadel +4 more
wiley +1 more source

