Results 51 to 60 of about 8,770 (226)

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Inability to Perform Retrograde Ureteroscopic Stone Treatment: A Postoperative Anatomical Change After Fleur-de-Lis Abdominoplasty

Case Reports in Urology
Abdominoplasty is a frequently performed elective procedure, often indicated for patients after substantial weight loss resulting in significant redundant skin. Closing techniques and the lifting of the mons pubis during abdominoplasty have been proposed
Parker L. Heger, Thomas F. Rashid, Lucas B. Vergamini, Bristol B. Whiles, Aaron Tverye, Wilson R. Molina   +5 more
doaj   +1 more source

Abdominoplasty Marking Instrument [PDF]

Revista Brasileira de Cirurgia Plástica, 2018
Introduction: Data from the International Society of Aesthetic Plastic Surgery indicate that abdominoplasty is the fourth most common plastic surgery performed worldwide. Several surgical techniques aim to restore the abdominal contour.
Sabina Aparecida Alvarez de Paiva, Heitor Carvalho Gomes, Denise Nicodemo, Elvio Bueno Garcia, Paulo Rodamilans Sanjuan, Patrícia Pimentel Pizzaro, Osvaldo Ribeiro Saldanha, Lydia Massako Ferreira   +7 more
doaj   +1 more source

Advanced Extractables and Leachables Assessment of Microcarriers Used for Adherent Cell Cultures

Biotechnology Journal, Volume 21, Issue 4, April 2026.
Graphical Abstract and Lay Summary We present a comprehensive workflow for the Extractables and Leachables (E & L) assessment of microcarriers used in adherent cell culture. Four key components are appied: experimental extractables testing (USP <665>), modelling of extractables release, process modelling, and safety assessment via biocompatibility and ...
Armin Hauk, Ina Pahl, Jonas Austerjost, Julia Hupfeld, Julia Bernfeld, Antonina Lavrentieva, Roberto Menzel   +6 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

, 1987
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1251/thumbnail ...
Giorgi, Gabriel
core   +2 more sources

Vaspin identified as a DNA‐binding serpin with functional consequences for protease inhibition

The FEBS Journal, Volume 293, Issue 7, Page 2119-2132, April 2026.
Vaspin is a serpin that is expressed in skin, adipose tissue, and liver. It binds to single‐ and double‐stranded DNA with high affinity. This binding is unaffected by mutation of the known heparin‐binding site, accelerates the inhibition of the inflammatory protease KLK7, and may contribute to vaspin's nuclear localization.
Kevin Möhlis, Abibe Useini, Heike Betat, Sonja Bonin, Helen Broghammer, Rima Nuwayhid, Stefan Langer, Mario Mörl, Norbert Sträter, John T. Heiker   +9 more
wiley   +1 more source

A US hospital budget impact analysis of a skin closure system compared with standard of care in hip and knee arthroplasty. [PDF]

, 2018
Background: Medicare\u27s mandatory bundle for hip and knee arthroplasty necessitates provider accountability for quality and cost of care to 90 days, and wound closure may be a key area of consideration.
Ferko, Nicole, Flener, Jana, Gargiulo, Jeanine, Hogan, Andrew, Hollmann, Sarah, Post, Zachary D., Sadik, Kay, Wurzelbacher, Steven   +7 more
core   +1 more source

Early Prediction of Scar Outcomes: A Prospective Study on the Predictive Value of 3‐Month Scar Assessments for 12‐Month Results

International Wound Journal, Volume 23, Issue 4, April 2026.
ABSTRACT Scar outcomes are traditionally evaluated at 12 months post‐surgery, yet early prediction of long‐term scar characteristics may facilitate timely interventions, enhance treatment strategies, shorten clinical trial durations, and improve patient outcomes.
Rena A. Li, Antoinette T. Nguyen, Bradley A. Melnick, Kelly C. Ho, Madeline J. O'Connor, Chad M. Teven, Thomas A. Mustoe, Robert D. Galiano   +7 more
wiley   +1 more source

Use of Infrared Thermography for Abdominoplasty Procedures in Patients with Extensive Subcostal Scars: A Preliminary Analysis

Plastic and Reconstructive Surgery, Global Open, 2023
Summary:. Subcostal scars may increase the risk of healing complications in abdominoplasty. The authors evaluated the use of thermography as a potential tool for patient selection and surgery planning to avoid complications and improve abdominoplasty ...
Rita Valença-Filipe, MD, Ricardo Vardasca, PhD, Carolina Magalhães, MSC, Joaquim Mendes, PhD, José Amarante, MD, PhD, António Costa-Ferreira, MD, PhD   +5 more
doaj   +1 more source

Prolonged Release of IL‐10 From Enzyme‐Mediated Poly‐l‐(Tyrosine‐co‐Phenylalanine) Nanocrystals Enhances Stability and Modulates Inflammatory Responses

Biopolymers, Volume 117, Issue 2, March 2026.
Schematic representation of enzyme‐mediated peptide nanocrystal formation and IL‐10 encapsulation, providing stabilized and sustained cytokine delivery that modulates macrophage phenotype and reduces inflammatory responses. ABSTRACT Protease‐catalyzed synthesis of a peptide composed of l‐tyrosine and l‐phenylalanine (2.2:1 M ratio) was achieved in a ...
Fátima Landa‐Tencle, Carmen G. Hernández‐Valencia, Fernando Guzmán‐Lagunes, Carmina Montiel, Yoan Cuellar‐Entenza, Carlos Guerrero‐Sánchez, Steffi Stumpf, Stephanie Hoeppener, Ulrich S. Schubert, Yessica Zamudio‐Cuevas, Roberto Sánchez‐Sánchez, Miquel Gimeno   +11 more
wiley   +1 more source