Results 51 to 60 of about 56,718 (251)

Circular Photocaged mRNA for Light‐induced Late‐stage Activation of Translation

Angewandte Chemie International Edition, EarlyView.
A clickable photo‐caged 5′ cap (CyCliCap) allows to make Cyclic Click Cap‐containing mRNA (CyCliCap‐mRNA) which is remarkably stable and translationally muted until irradiated, allowing for late‐stage activation of translation in cells by light. ABSTRACT mRNA is a new medical modality as vaccine and raises hopes to become a protein replacement agent ...
Bayram Terzi, Greta Charlotte Dahm, Kristoffer Heintz, Martin Sumser, Yasuaki Kimura, Hiroshi Abe, Andrea Rentmeister   +6 more
wiley   +1 more source

Stabilization of PUFA‐Rich Mayonnaise Against Lipid Oxidation: A Review of the Last Three Decades of Research

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Mayonnaise, a widely consumed oil‐in‐water emulsion, is highly susceptible to lipid oxidation due to its high content of polyunsaturated fatty acids (PUFAs) and the presence of pro‐oxidant factors such as low pH and iron from egg yolk. Over the past three decades, extensive research has focused on understanding oxidation mechanisms, analytical
Sakhi Ghelichi, Betül Yesiltas, Charlotte Jacobsen   +2 more
wiley   +1 more source

The morphology of the oval window in Paranthropus robustus compared to humans and other modern primates

The Anatomical Record, EarlyView.
Abstract The oval window (OW) is an opening connecting the inner and middle ear. Its area has been shown to consistently scale with body mass (BM) in primates, and has been used alongside semi‐circular canal (SCC) size to differentiate Homo sapiens and fossil hominins, including Paranthropus robustus.
Ruy Fernandez, José Braga
wiley   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Feasibility Study for Application of Digitized Henize Mt. Wilson Michigan Southern Sky Hα$$ \boldsymbol{\alpha} $$ Survey Low‐Dispersive Spectral Plates for Searches for Anomalous and Highly Redshifted Objects

Astronomische Nachrichten, EarlyView.
ABSTRACT The goal of this study is to confirm the feasibility of the use of digitized low dispersive MtWilson Michigan Southern Sky Hα$$ \alpha $$ survey astronomical photographic plates for modern astrophysical research. The detection of highly redshifted objects, such as early galaxies and quasars, is fundamental to understanding the universe's ...
Tauseef Ahmad Zafar, René Hudec, Marta Mara Merono Vidagany, Fehmi Mejri   +3 more
wiley   +1 more source

Speckle Observations With PISCO in Calern (France): III. Astrometric Measurements of Visual Double Stars in 2019 and New or Revised Orbits for STT531 AB, STT77 AB, STF1338 AB, COU1746, STT260, A1109 AB, HU1291, and A632 AB

Astronomische Nachrichten, EarlyView.
ABSTRACT We present relative astrometric measurements of visual double stars, made in 2019 with the speckle camera PISCO at the 1‐m Epsilon telescope of the C2PU facility (Observatoire de la Côte d'Azur, Calern site). Our observing list contains orbital couples as well as double stars whose motion is still uncertain.
J.‐L. Prieur, M. Scardia, J.‐P. Rivet, E. Aristidi, J. F. Ling, L. Piccotti, L. Pansecchi, R. W. Argyle, L. Abe, P. Bendjoya, L. Maccarini, D. Vernet   +11 more
wiley   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu, Eduardo Barbieri, Arianna Minzoni, Shriarjun Shastry, Jacob P. LeBarre, Qingbo Shu, Taufika Williams, Xuanwen Li, Divya Chandra, Xuankuo Xu, Jerome Bill, David Roush, Joseph Taris, Patrick Gilbert, Andre Kiesewetter, Oliver Rammo, Michael Schulte, Christopher Major, Trina Mouchahoir, Steven Cramer, Cristiana Boi, Ruben G. Carbonell, Abraham Lenhoff, Stefano Menegatti   +23 more
wiley   +1 more source

AB GELECEĞİNİ ARIYOR: AB Konvansiyonu

Marmara Üniversitesi Avrupa Topluluğu Enstitüsü Avrupa Araştırmaları Dergisi, 2015
The European Union has stepped up through a phase in which Single European Act, the EU Treaty, Amsterdam Treaty and Nice Treaty became important landmarks. Together with the Rome Treaty these establishing treaties put objectives and destination of the Union, which are well-known characteristics of the EU, -like peace and solidarity expressed in ...
openaire   +3 more sources

Evidence for adaptive explanations of semelparity in animals

Biological Reviews, EarlyView.
ABSTRACT Semelparity, the reproductive strategy of reproducing once, is widespread but uncommon in animals. Classes of models to explain the evolution of semelparity are based either on age structure and mortality schedules – demographic models in which high post‐reproductive mortality risk favours high reproductive effort and semelparity results from ...
Diana O. Fisher, Roberto Salguero‐Gómez   +1 more
wiley   +1 more source

A morada da língua portuguesa

Ensaio, 2014
Temos raízes latinas muito sólidas, o que não foi suficiente para que o Acordo Ortográfico de Unificação da Língua Portuguesa, assinado em 1990, alcançasse a unanimidade desejável.
Arnaldo Niskier
doaj   +1 more source