Adipocyte‐derived palmitic acid induces ZDHHC15‐mediated PPARγ S‐palmitoylation at Cys159, triggering its proteasomal degradation and promoting breast cancer malignancy with rosiglitazone resistance. Inhibition of PPARγ S‐palmitoylation by 2‐bromopalmitate suppresses breast cancer progression and synergistically enhances rosiglitazone efficacy ...
Geon Ho Moon +6 more
wiley +1 more source
Erratum: Global population structure of Shiga toxin-producing <i>Escherichia coli</i> O103:H2 and the variation in their major virulence factor-encoding genetic elements. [PDF]
Taniguchi I +18 more
europepmc +1 more source
ZDHHC11-mediated palmitoylation of viral envelope protein restricts dengue virus replication: implication for the development of universal anti-flavivirus therapeutic strategies. [PDF]
Lai M +8 more
europepmc +1 more source
Coinvasional disruptions to island pollinator networks
Abstract Biological invasions can adversely affect pollinator diversity by threatening the maintenance of animal‐pollinated plant communities. Although most studies have examined single invasive species, accelerating species introductions driven by global trade highlight the need to understand how multiple co‐occurring invaders jointly influence ...
Marta Quitián +5 more
wiley +1 more source
A combinatorial synthetic strategy for developing genome-editing protein-delivery agents targeting mouse retina. [PDF]
Zhang J +19 more
europepmc +1 more source
Assessing and strengthening community‐based coastal governance
Abstract Community‐based coastal governance is essential for biodiversity conservation and sustainable livelihoods, yet many communities continue to face significant challenges in establishing and sustaining effective governance systems. We sought to improve understanding of the current status of community‐based coastal governance across five countries
Mark Andrachuk +21 more
wiley +1 more source
China-Japan joint symposium on disasters and public health crises: learnings from the Fukushima nuclear power plant accident and COVID-19 pandemic. [PDF]
Matsumoto C +7 more
europepmc +1 more source
Pest‐preservation paradox among insects
The pest‐preservation paradox is a non‐binary perspective that insects range from those that are harmful and requiring management on the one side, to those requiring conservation intervention on the opposite end of the spectrum. Importantly, the vast majority of insects occur somewhere in the center of the two extremes, and their position along the ...
Michael J. Samways +3 more
wiley +1 more source
AKT-mediated phosphorylation of ZDHHC5 promotes NOD1 palmitoylation and innate immune signaling. [PDF]
Mi S +5 more
europepmc +1 more source
Summary Background and objectives The relationship between atopic dermatitis (AD), weight, height, and body mass index (BMI) in children and adolescents and the impact of systemic treatments is controversial. We report the distribution of weight, height, and BMI in the German TREATkids cohort compared to a standardized German cohort (Kromeyer‐Hauschild)
Barbara Kind +17 more
wiley +1 more source

