Colorectal cancer (CRC) shows high molecular heterogeneity, yet single‐cell data from Japanese patients are limited. We performed scRNA‐seq on tumors and adjacent normal tissues from four Japanese CRC patients and identified a shared malignant cell cluster with high KCNQ1OT1 expression and reduced RASSF6 levels.
Sadahiro Iwabuchi +15 more
wiley +1 more source
Evolution into chaos - Implications of the trade-off between transmissibility and immune evasion. [PDF]
Sayyar G, Garab Á, Röst G.
europepmc +1 more source
Drivers and Consequences of Size Declines in Unicells
Previous syntheses concluded that metabolic allometric scaling is unusually steep (> 1) in unicells but here we show that this steepness is an artefact of laboratory studies that confound cell size with cell population density. Once this density effect is accounted for, metabolic scaling is ~0.86 in unicells.
Dustin J. Marshall +5 more
wiley +1 more source
Existence and uniqueness of solutions for fuzzy fractional integro-differential equations with boundary conditions. [PDF]
K A, V P, Kausar N, Salman MA.
europepmc +1 more source
The status of thegn in late Anglo‐Saxon England
This article considers how the term ‘thegn’ was used in tenth‐ and eleventh‐century England. Although commonly thought to indicate members of a face‐to‐face service aristocracy with specific attributes, it has resisted close definition. Examination of references to anonymous thegns in administrative and legal texts suggests that the people meant were ...
Richard Purkiss
wiley +1 more source
Viscoelastic Creep of 3D-Printed Polyethylene Terephthalate Glycol Samples. [PDF]
Stankevics L +4 more
europepmc +1 more source
SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity
The SARS‐CoV‐2 nucleocapsid (N) protein is not only the specific viral RNA packaging protein, but also acts as an RNA chaperone, facilitating RNA folding. We show that it facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone.
Sabrina Babl +11 more
wiley +1 more source
Development of Alginate/Carboxymethylcellulose Films Incorporated with <i>Canavalia ensiformis</i> Lectin (ConA) with Angiogenic Properties. [PDF]
Santos MHC +13 more
europepmc +1 more source
The supervised clustering of metabolic dysfunction‐associated steatotic liver disease (MASLD) using a SHapley Additive exPlanations (SHAP)‐converted matrix reveals distinct subpopulations that improved risk stratification for new onset of chronic kidney disease (CKD).
Itaru Hosaka +14 more
wiley +1 more source
Unraveling ShuA detergent-induced colloidal behavior in solution: A comprehensive SEC-MALS, SAXS, and SANS study. [PDF]
Pozza A +7 more
europepmc +1 more source

