Results 231 to 240 of about 158,981 (349)
Abstract Objective Timely diagnosis and effective treatment of Lennox–Gastaut syndrome (LGS) improve prognosis and lower health care costs, but the transition from infantile epileptic spasms syndrome (IESS) to LGS is highly variable and insidious. Objective biomarkers are needed to monitor this progression and guide clinical decision‐making. Methods We
Blanca Romero Milà +11 more
wiley +1 more source
Optical observations of embolism in three conifers overestimate the vulnerability of stem xylem to hydraulic dysfunction. [PDF]
Losso A, Feng F, Beikircher B, Mayr S.
europepmc +1 more source
No time for spruce: rapid dampening of circadian rhythms in Picea abies (L. Karst).
N. Gyllenstrand +7 more
semanticscholar +1 more source
Abstract Recurrent seizures have such a negative impact upon the lives of persons with epilepsy that their prevention is a constant preoccupation of neurologists. Despite the large number of antiseizure medications (ASMs) currently available and of publications on their putative efficacy, adverse effects, and order of preference to start treatment ...
André Palmini +2 more
wiley +1 more source
Abstract Objective A Pediatric Investigation Plan (PIP) implemented under the European Pediatric Regulation (EC No. 1901/2006) aims to ensure early and systematic evaluation of medicines for children. We analyze PIPs for antiseizure medications (ASMs) submitted to the European Medicines Agency (EMA) since 2006, characterizing their content, focusing on
Valeria Agostini, Stéphane Auvin
wiley +1 more source
Provenance Variation in Functional Traits of European Forest Trees: Meta-Analysis Reveals Effects of Taxa and Age Despite Critical Research Gaps. [PDF]
Aspalter S +4 more
europepmc +1 more source
Clinical trajectories and medication response in TBC1D24‐related epilepsies
Abstract Objective Biallelic variants in TBC1D24 represent a rare cause of epilepsy and neurodevelopmental disorders, including severe developmental and epileptic encephalopathies. Here, we present the first attempt to delineate the longitudinal disease histories and effectiveness of antiseizure medications (ASMs) in TBC1D24‐related disorders.
Ealing Mondragon +9 more
wiley +1 more source
Experimental Study on Mechanical Properties of European Oak and Norway Spruce Clear Wood. [PDF]
Gambarelli S +3 more
europepmc +1 more source
Abstract Consensus‐based recommendations (CBRs) are essential for health care decision‐making when evidence is limited or conflicting. They can be developed using established methodologies such as the Delphi technique, the nominal group technique (NGT), and the RAND Corporation/University of California Los Angeles (UCLA) Appropriateness Method (RAM ...
Rowan Haffner +14 more
wiley +1 more source

