ABIETANE DITERPENOIDS FROM PLECTRANTHUS GRANDIDENTATUS [PDF]
Phytochemistry, 1997 The acetone extract of the whole plant of Plectranthus grandidentatus provided the already known abietanes royleanone, 6,7-dehydroroyleanone, horminone, 6β-hydroxyroyleanone, 7α-acetoxy-6β-hydroxyroyleanone and the abietane dimers grandidone C ...
Batista, Olga +6 more
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Plectranthus-derived Abietanes as Protein Kinase C-δ Activators: In Silico Design, Human Serum Albumin Interaction, and Stability Evaluation. [PDF]
Chem BiodiversABSTRACT Cancer remains a major global health challenge. Among protein kinases (PKCs), PKC‐δ acts as a tumor suppressor in colon cancer and represents a valuable therapeutic target. Human serum albumin (HSA) is gaining attention as an efficient drug carrier, while Plectranthus spp. offers a rich source of bioactive compounds.
Isca VMS +4 more
europepmc +2 more sources
Electrochemical oxidation of abietanes
Proceedings of 7th International Electronic Conference on Medicinal Chemistry, 2021 Pine trees are coniferous, from which we can extract wood, raw tall oil, wood gum, and gum. Through the distillation of gum, we can acquire turpentine and colophony. Colophony is a complex mixture of neutral terpenes and acidic diterpenes, including abietanes, which are tricyclic diterpenoids to which abietic acid (AA) and dehydroabietic acid (DHA ...
Inês Martins +2 more
openaire +4 more sources
Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System. [PDF]
ChemistryOpenAbietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Afroz M +10 more
europepmc +2 more sources
Flukicidal effects of abietane diterpenoid derived analogues against the food borne pathogen Fasciola hepatica. [PDF]
, 2022 Control of liver fluke infections remains a significant challenge in the livestock sector due to widespread distribution of drug resistant parasite populations.
Gilda Padalino
core +7 more sources
Phytochemical and Bioactivity Studies from Plectranthus ecklonii†
Medical Sciences Forum, 2022 Plectranthus is a well-known genus belonging to the Lamiaceae family and is mainly distributed in tropical areas of the globe. Furthermore, Plectranthus species are particularly rich in phenolic compounds and abietane-type diterpenes, such as royleanones,
Márcia Santos Filipe +4 more
doaj +1 more source
Plants, 2021 Medicinal plants of the Plectranthus genus (Lamiaceae) are well known for their ethnomedicinal applications. Plectranthus madagascariensis, which is native to South Africa, is traditionally used in the treatment of respiratory conditions, scabies, and ...
Kadidiatou O. Ndjoubi +7 more
doaj +1 more source
Determination of the molecular signature of fossil conifers by experimental palaeochemotaxonomy – Part 1: The Araucariaceae family [PDF]
Biogeosciences, 2013 Twelve species of the conifer family Araucariaceae, including Araucaria (6 species), Agathis (3 species) and Wollemia (1 species) genera, were submitted to artificial maturation by confined pyrolysis.
Y. Lu, Y. Hautevelle, R. Michels
doaj +1 more source
Abietane and Ent-abietane Diterpenoids from the Leaves of Suregada Zanzibariensis
, 2022 NMR raw data (FIDs), processed mestrenova files and NMReDATA files for the isolated compounds.
Kalenga, Thobias M. +13 more
openaire +2 more sources
Antibacterial profiling of abietane-type diterpenoids [PDF]
Bioorganic & Medicinal Chemistry, 2017 Abietic and dehydroabietic acid are interesting diterpenes with a highly diverse repertoire of associated bioactivities. They have, among others, shown antibacterial and antifungal activity, potentially valuable in the struggle against the increasing antimicrobial resistance and imminent antibiotic shortage.
Andreas Helfenstein +8 more
openaire +3 more sources