Results 101 to 110 of about 2,725,948 (284)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The Views of Interns of Tabriz University of Medical Sciences Iran Regarding Practical Education and Clinical Skills Based on the Basic Minimum Competencies Statement of General Practitioners in Iran [PDF]
Strides in Development of Medical Education, 2016 Background & Objective: Medical education is based on both practical skills and theoretical knowledge Clinical skills training is an essential component of medical education One of the best evaluation methods for educational systems is to determine ...
Mahasti Alizadeh +3 more
doaj
, 2010 Ability testing has been used in education for about a 100 years, and in some countries its use has been extensive. During that time, the concept of ability has been refined as has its measurement. Mistakes have been made and our understanding is still evolving.
openaire +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Polylinguality and Transcultural Practices, 2009 This article is devoted the differential model of the Russian phonetics. The diagnostic of the students phonetics skills is proposed the necessary to create the test of the phonetics skills.
S S Pashkovskaia
doaj
Research of level of formed knowledge, abilities and skills on basket-ball for the students of faculty of physical education. [PDF]
Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2011 The results of a zero control of students of faculty of physical education are presented. The estimation of theoretical knowledge's is conducted, abilities and skills on basket-ball for the students of a 1 course of directions of preparation «Physical ...
Kovalenko J.A.
doaj
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Dream as a subject of psychological research [PDF]
Психологическая наука и образование (2007. Online), 2014 We discuss the main theoretical concepts of a dream: dream definitions, ideas about its genesis, functions, dream location in the structure of activity. We analyze the similarities and differences between the approaches.
P.A. Egorova,
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source