Results 121 to 130 of about 2,725,948 (284)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Modeling Provider Knowledge, Skills, and Abilities (KSA) [PDF]
No abstract ...
Levin, Dana, Mcguire, Kerry M.
core +1 more source
Adolescent Legal Competence in Court [PDF]
, 2006 This brief details findings from the first comprehensive assessment of juvenile capacities to participate in criminal proceedings using measures of both trial-related abilities and developmental ...
core
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Swimming as important factor of development of physical abilities [PDF]
Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2012 The current state of health and physical fitness of young people, the complex of issues regarding the development of sports and mass swimming in Ukraine, in particular regarding training the ability to swim of the population and its conscripts have been ...
Popadin V.V. +2 more
doaj
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2013 It is shown that practice of teaching of discipline «Physical education» does not provide forming of volume of abilities, sufficient for the origin of athletic activity.
S.I. Belykh, S.A. Chernigovskaia
doaj
Ostension and Demonstrative Reference [PDF]
, 2014 . The strong similarity between the use of ostension and that of a simple demonstrative to predicate something of an object seems to conflict with equally strong intuitions according to which, while “this” does usually refer to an ...
Stefanov, Gheorghe
core
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source